Literature DB >> 20882068

The function of DNA topoisomerase IIβ in neuronal development.

Xin Heng1, Wei-Dong Le.   

Abstract

Type II DNA topoisomerases (Tops) are ATP-dependent enzymes that catalyze topological transformations of genomic DNA by the transport of one DNA double helix through another. In mammals, there are 2 isoforms of DNA Top II, termed Top IIα and Top IIβ. The IIβ isoform is abundantly expressed in cells that have undergone the final cell division and are committed to differentiation into neuronal cells. In recent years, there have been accumulating studies showing the significant role of Top IIβ in neuronal development through regulating expression of certain genes in cells committed to the neuronal fate after the final division. These genes are involved in the processes of neuronal differentiation, migration, axon guidance and so on. The present review mainly focused on the research progress on the role of Top IIβ in neuronal development over the recent decades.

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Year:  2010        PMID： 20882068      PMCID： PMC5560355          DOI： 10.1007/s12264-010-0625-9

Source DB:  PubMed          Journal:  Neurosci Bull        ISSN： 1995-8218            Impact factor:   5.203


  29 in total

1.  DNA topoisomerase IIbeta and neural development.

Authors:  X Yang; W Li; E D Prescott; S J Burden; J C Wang
Journal:  Science       Date:  2000-01-07       Impact factor: 47.728

2.  Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

Authors:  F H Drake; G A Hofmann; H F Bartus; M R Mattern; S T Crooke; C K Mirabelli
Journal:  Biochemistry       Date:  1989-10-03       Impact factor: 3.162

3.  Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta.

Authors:  Yi Lisa Lyu; James C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-28       Impact factor: 11.205

4.  The 180-kDa isoform of topoisomerase II is localized in the nucleolus and belongs to the structural elements of the nucleolar remnant.

Authors:  N Zini; A M Martelli; P Sabatelli; S Santi; C Negri; G C Astaldi Ricotti; N M Maraldi
Journal:  Exp Cell Res       Date:  1992-06       Impact factor: 3.905

5.  A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

Authors:  Bong-Gun Ju; Victoria V Lunyak; Valentina Perissi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld
Journal:  Science       Date:  2006-06-23       Impact factor: 47.728

6.  Role of DNA topoisomerase IIbeta in neurite outgrowth.

Authors:  Alam Nur-E-Kamal; Sally Meiners; Ijaz Ahmed; Anna Azarova; Chao-po Lin; Yi Lisa Lyu; Leroy F Liu
Journal:  Brain Res       Date:  2007-04-19       Impact factor: 3.252

Review 7.  Appendix. II: Alignment of primary sequences of DNA topoisomerases.

Authors:  P R Caron; J C Wang
Journal:  Adv Pharmacol       Date:  1994

8.  Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.

Authors:  C A Austin; J H Sng; S Patel; L M Fisher
Journal:  Biochim Biophys Acta       Date:  1993-03-20

9.  Ebf1 controls early cell differentiation in the embryonic striatum.

Authors:  S Garel; F Marín; R Grosschedl; P Charnay
Journal:  Development       Date:  1999-12       Impact factor: 6.868

10.  Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24.

Authors:  J R Jenkins; P Ayton; T Jones; S L Davies; D L Simmons; A L Harris; D Sheer; I D Hickson
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971
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  9 in total

1.  6,6'-Dihydroxythiobinupharidine as a poison of human type II topoisomerases.

Authors:  Esha D Dalvie; Jacob Gopas; Avi Golan-Goldhirsh; Neil Osheroff
Journal:  Bioorg Med Chem Lett       Date:  2019-06-04       Impact factor: 2.823

Review 2.  Topoisomerase II and leukemia.

Authors:  Maryjean Pendleton; R Hunter Lindsey; Carolyn A Felix; David Grimwade; Neil Osheroff
Journal:  Ann N Y Acad Sci       Date:  2014-02-03       Impact factor: 5.691

3.  Etoposide quinone is a covalent poison of human topoisomerase IIβ.

Authors:  Nicholas A Smith; Jo Ann W Byl; Susan L Mercer; Joseph E Deweese; Neil Osheroff
Journal:  Biochemistry       Date:  2014-05-02       Impact factor: 3.162

4.  Smoothed Potential MD Simulations for Dissociation Kinetics of Etoposide To Unravel Isoform Specificity in Targeting Human Topoisomerase II.

Authors:  Jissy A Kuriappan; Neil Osheroff; Marco De Vivo
Journal:  J Chem Inf Model       Date:  2019-09-09       Impact factor: 4.956

5.  DNA topoisomerase IIIβ promotes cyst generation by inducing cyst wall protein gene expression in Giardia lamblia.

Authors:  Chin-Hung Sun; Shih-Che Weng; Jui-Hsuan Wu; Szu-Yu Tung; Li-Hsin Su; Meng-Hsuan Lin; Gilbert Aaron Lee
Journal:  Open Biol       Date:  2020-02-05       Impact factor: 6.411

6.  Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37.

Authors:  Shangyao Qin; Yimin Yuan; Xiao Huang; Zijian Tan; Xin Hu; Hong Liu; Yingyan Pu; Yu-Qiang Ding; Zhida Su; Cheng He
Journal:  Nucleic Acids Res       Date:  2022-08-27       Impact factor: 19.160

7.  DNA topoisomerase II is involved in regulation of cyst wall protein genes and differentiation in Giardia lamblia.

Authors:  Bo-Chi Lin; Li-Hsin Su; Shih-Che Weng; Yu-Jiao Pan; Nei-Li Chan; Tsai-Kun Li; Hsin-Chih Wang; Chin-Hung Sun
Journal:  PLoS Negl Trop Dis       Date:  2013-05-16

8.  DNA topoisomerase IIβ stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression.

Authors:  Merve Zaim; Sevim Isik
Journal:  Stem Cell Res Ther       Date:  2018-04-25       Impact factor: 6.832

Review 9.  The Roles of DNA Topoisomerase IIβ in Transcription.

Authors:  Ram Madabhushi
Journal:  Int J Mol Sci       Date:  2018-06-29       Impact factor: 5.923
  9 in total

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