| Literature DB >> 2088200 |
M J Everett1, I Chopra, P M Bennett.
Abstract
Induction of the cloned ampC Citrobacter freundii beta-lactamase in Escherichia coli by 6-aminopenicillanic acid was prevented by periplasmic TEM beta-lactamase in the same cell. In contrast, cytoplasmic TEM beta-lactamase did not prevent induction. This result implies that entry of the beta-lactam into the cytoplasm is not necessary for induction of ampC.Entities:
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Year: 1990 PMID: 2088200 PMCID: PMC172076 DOI: 10.1128/AAC.34.12.2429
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191