UNLABELLED: Prostate cancer is a major health threat for men. For over five years, the U.S. National Cancer Institute has performed prostate biopsies with a magnetic resonance imaging (MRI)-guided robotic system. PURPOSE: A retrospective evaluation methodology and analysis of the clinical accuracy of this system is reported. METHODS: Using the pre and post-needle insertion image volumes, a registration algorithm that contains a two-step rigid registration followed by a deformable refinement was developed to capture prostate dislocation during the procedure. The method was validated by using three-dimensional contour overlays of the segmented prostates and the registrations were accurate up to 2 mm. RESULTS: It was found that tissue deformation was less of a factor than organ displacement. Out of the 82 biopsies from 21 patients, the mean target displacement, needle placement error, and clinical biopsy error was 5.9 mm, 2.3 mm, and 4 mm, respectively. CONCLUSION: The results suggest that motion compensation for organ displacement should be used to improve targeting accuracy.
UNLABELLED: Prostate cancer is a major health threat for men. For over five years, the U.S. National Cancer Institute has performed prostate biopsies with a magnetic resonance imaging (MRI)-guided robotic system. PURPOSE: A retrospective evaluation methodology and analysis of the clinical accuracy of this system is reported. METHODS: Using the pre and post-needle insertion image volumes, a registration algorithm that contains a two-step rigid registration followed by a deformable refinement was developed to capture prostate dislocation during the procedure. The method was validated by using three-dimensional contour overlays of the segmented prostates and the registrations were accurate up to 2 mm. RESULTS: It was found that tissue deformation was less of a factor than organ displacement. Out of the 82 biopsies from 21 patients, the mean target displacement, needle placement error, and clinical biopsy error was 5.9 mm, 2.3 mm, and 4 mm, respectively. CONCLUSION: The results suggest that motion compensation for organ displacement should be used to improve targeting accuracy.
Authors: Axel Krieger; Robert C Susil; Cynthia Ménard; Jonathan A Coleman; Gabor Fichtinger; Ergin Atalar; Louis L Whitcomb Journal: IEEE Trans Biomed Eng Date: 2005-02 Impact factor: 4.538
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Authors: Helen Xu; Andras Lasso; Siddharth Vikal; Peter Guion; Axel Krieger; Aradhana Kaushal; Louis L Whitcomb; Gabor Fichtinger Journal: Proc SPIE Int Soc Opt Eng Date: 2010-02-23
Authors: A E Wefer; H Hricak; D B Vigneron; F V Coakley; Y Lu; J Wefer; U Mueller-Lisse; P R Carroll; J Kurhanewicz Journal: J Urol Date: 2000-08 Impact factor: 7.450
Authors: Jan Egger; Junichi Tokuda; Laurent Chauvin; Bernd Freisleben; Christopher Nimsky; Tina Kapur; William Wells Journal: Int J Med Robot Date: 2012-02-28 Impact factor: 2.547
Authors: Helen Xu; Andras Lasso; Peter Guion; Axel Krieger; Aradhana Kaushal; Anurag K Singh; Peter A Pinto; Jonathan Coleman; Robert L Grubb; Jean-Baptiste Lattouf; Cynthia Menard; Louis L Whitcomb; Gabor Fichtinger Journal: Int J Comput Assist Radiol Surg Date: 2013-03-27 Impact factor: 2.924