| Literature DB >> 20878923 |
Chaoyong Zhao1, Xiangdong Zhu, Kailu Liang, Jietao Ding, Zhou Xiang, Hongsong Fan, Xingdong Zhang.
Abstract
In this study, a slurry foaming method was developed to fabricate porous titanium, and two different surface treatments were applied to investigate their effects on the osteoinduction of the implants. Three types of implants, that was porous titanium with no treatment, with chemical-thermal treatment (CTPT), and with acid-alkali treatment (AAPT), were implanted in the dorsal muscles of adult dogs for 3 and 5 months. After implantation for 3 months, new bone was only found in the inner pores of AAPT by histological analysis and field emission scanning electron microscopy observation. After implantation for 5 months, new bone was also found in CTPT, but it was absent in AAPT. This study not only confirmed that porous titanium with appropriate surface treatments could possess osteoinduction but also showed that its osteoinductive potential was tightly related to the surface treatment. As a simpler method, acid-alkali treatment could endow porous titanium with faster osteoinduction, and AAPT might have potential in clinical application.Entities:
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Year: 2010 PMID： 20878923 DOI： 10.1002/jbm.b.31728
Source DB: PubMed Journal: J Biomed Mater Res B Appl Biomater ISSN： 1552-4973 Impact factor: 3.368