| Literature DB >> 2087878 |
T Oka1, T Honda, K Ohkuma, M Sakoh, S Nonaka.
Abstract
We evaluated the possibility of application of carboxy vinylpolymer (CVP) to influenza vaccine for the improvement of immune response. Our result shows that CVP induces good immune responses after inoculation of vaccines to mice both subcutaneously, intraperitoneally, and intranasally. Considering the efficacy and safety, intranasal administration of the CVP-coupled vaccine may be the best route of immunization.Entities:
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Year: 1990 PMID： 2087878 DOI： 10.1016/0264-410x(90)90011-a
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641