BACKGROUND: Shift work with sleep disruption is a systemic stressor that may possibly be associated with blood pressure dysregulation and hypertension. PURPOSE: We hypothesize that rotation to a simulated night shift with sleep deprivation will produce blood pressure elevations in persons at risk for development of hypertension. METHOD: We examined the effects of a simulated night shift on resting blood pressure in 51 diurnal young adults without current hypertension. Resting blood pressure was monitored throughout a 24-h period of total sleep deprivation with sustained cognitive work. Twelve participants (23.5%) reported one or more parents with a diagnosis of hypertension. Ten participants were classified as prehypertensive by JNC-7 criteria. Only two prehypertensive subjects reported parental hypertension. RESULTS: Results indicate that, as the night shift progressed, participants with a positive family history of hypertension showed significantly higher resting diastolic blood pressure than those with a negative family history of hypertension (p = 0.007). Prehypertensive participants showed elevated blood pressure throughout the study. CONCLUSION: These data suggest that rotation to a simulated night shift with sleep deprivation may contribute to blood pressure dysregulation in persons with a positive family history of hypertension.
BACKGROUND: Shift work with sleep disruption is a systemic stressor that may possibly be associated with blood pressure dysregulation and hypertension. PURPOSE: We hypothesize that rotation to a simulated night shift with sleep deprivation will produce blood pressure elevations in persons at risk for development of hypertension. METHOD: We examined the effects of a simulated night shift on resting blood pressure in 51 diurnal young adults without current hypertension. Resting blood pressure was monitored throughout a 24-h period of total sleep deprivation with sustained cognitive work. Twelve participants (23.5%) reported one or more parents with a diagnosis of hypertension. Ten participants were classified as prehypertensive by JNC-7 criteria. Only two prehypertensive subjects reported parental hypertension. RESULTS: Results indicate that, as the night shift progressed, participants with a positive family history of hypertension showed significantly higher resting diastolic blood pressure than those with a negative family history of hypertension (p = 0.007). Prehypertensiveparticipants showed elevated blood pressure throughout the study. CONCLUSION: These data suggest that rotation to a simulated night shift with sleep deprivation may contribute to blood pressure dysregulation in persons with a positive family history of hypertension.
Authors: Andrew Sherwood; Patrick R Steffen; James A Blumenthal; Cynthia Kuhn; Alan L Hinderliter Journal: Am J Hypertens Date: 2002-02 Impact factor: 2.689
Authors: Peter L Franzen; Peter J Gianaros; Anna L Marsland; Martica H Hall; Greg J Siegle; Ronald E Dahl; Daniel J Buysse Journal: Psychosom Med Date: 2011-09-23 Impact factor: 4.312
Authors: Maple M Fung; Katherine Peters; Susan Redline; Michael G Ziegler; Sonia Ancoli-Israel; Elizabeth Barrett-Connor; Katie L Stone Journal: Hypertension Date: 2011-08-29 Impact factor: 10.190
Authors: James A McCubbin; Heidi M Zinzow; Melissa A Hibdon; Aaron W Nathan; Anastasia V Morrison; Gregg W Hayden; Caitlyn Lindberg; Fred S Switzer Journal: Cardiovasc Psychiatry Neurol Date: 2016-06-15