PURPOSE: To describe the mechanics and possible clinical importance of left ventricular (LV) rotation, exemplify techniques to quantify LV rotation and illustrate the temporal relationship of cardiac pressures, electrocardiogram and LV rotation. MATERIALS AND METHODS: Review of the literature combined with selected examples of echocardiographic measurements. RESULTS: Rotation of the left ventricle around its longitudinal axis is an important but thus far neglected aspect of the cardiac cycle. LV rotation during systole maximizes intracavitary pressures, increases stroke volume, and minimizes myocardial oxygen demand. Shearing and restoring forces accumulated during systolic twisting are released during early diastole and result in diastolic LV untwisting or recoil promoting early LV filling. LV twist and untwist are disturbed in a number of cardiac diseases and can be influenced by several therapeutic interventions by altering preload, afterload, contractility, heart rate, and/or sympathetic tone. CONCLUSIONS: The concept of LV twisting and untwisting closely linking LV systolic and diastolic function may carry potential diagnostic and therapeutic importance for the management of critically ill patients. Future clinical studies need to address the feasibility of assessing LV twist and untwist as well as the relevance of its therapeutic modulation in critically ill patients.
PURPOSE: To describe the mechanics and possible clinical importance of left ventricular (LV) rotation, exemplify techniques to quantify LV rotation and illustrate the temporal relationship of cardiac pressures, electrocardiogram and LV rotation. MATERIALS AND METHODS: Review of the literature combined with selected examples of echocardiographic measurements. RESULTS: Rotation of the left ventricle around its longitudinal axis is an important but thus far neglected aspect of the cardiac cycle. LV rotation during systole maximizes intracavitary pressures, increases stroke volume, and minimizes myocardial oxygen demand. Shearing and restoring forces accumulated during systolic twisting are released during early diastole and result in diastolic LV untwisting or recoil promoting early LV filling. LV twist and untwist are disturbed in a number of cardiac diseases and can be influenced by several therapeutic interventions by altering preload, afterload, contractility, heart rate, and/or sympathetic tone. CONCLUSIONS: The concept of LV twisting and untwisting closely linking LV systolic and diastolic function may carry potential diagnostic and therapeutic importance for the management of critically illpatients. Future clinical studies need to address the feasibility of assessing LV twist and untwist as well as the relevance of its therapeutic modulation in critically illpatients.
Authors: Yuichi Notomi; Zoran B Popovic; Hirotsugu Yamada; Don W Wallick; Maureen G Martin; Stephanie J Oryszak; Takahiro Shiota; Neil L Greenberg; James D Thomas Journal: Am J Physiol Heart Circ Physiol Date: 2007-11-21 Impact factor: 4.733
Authors: Partho P Sengupta; Vijay K Krishnamoorthy; Josef Korinek; Jagat Narula; Mani A Vannan; Steven J Lester; Jamil A Tajik; James B Seward; Bijoy K Khandheria; Marek Belohlavek Journal: J Am Soc Echocardiogr Date: 2007-05 Impact factor: 5.251
Authors: Bas M van Dalen; Osama I I Soliman; Wim B Vletter; Folkert J ten Cate; Marcel L Geleijnse Journal: Echocardiography Date: 2008-11-24 Impact factor: 1.724
Authors: Massimo Antonelli; Marc Bonten; Jean Chastre; Giuseppe Citerio; Giorgio Conti; J Randall Curtis; Daniel De Backer; Goran Hedenstierna; Michael Joannidis; Duncan Macrae; Jordi Mancebo; Salvatore M Maggiore; Alexandre Mebazaa; Jean-Charles Preiser; Patricia Rocco; Jean-François Timsit; Jan Wernerman; Haibo Zhang Journal: Intensive Care Med Date: 2012-01-20 Impact factor: 17.440