Literature DB >> 20877896

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles.

Emanuela Occhipinti1, Paolo Verderio, Antonino Natalello, Elisabetta Galbiati, Miriam Colombo, Serena Mazzucchelli, Agnese Salvadè, Paolo Tortora, Silvia Maria Doglia, Davide Prosperi.   

Abstract

We present the synthesis of trastuzumab-functionalized pegylated iron oxide nanoparticles and provide an FTIR-based approach to gain a direct evidence of the actual conservation of the native structure of conjugated antibody. Their target-selectivity to specific cancer cell receptors has been also assessed.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20877896     DOI： 10.1039/c0nr00436g

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  6 in total

1.  Anti-CEA loaded maghemite nanoparticles as a theragnostic device for colorectal cancer.

Authors:  Mariana Campos da Paz; Maria de Fátima M Almeida Santos; Camila M B Santos; Sebastião W da Silva; Lincoln Bernardo de Souza; Emília C D Lima; Renata C Silva; Carolina M Lucci; Paulo César Morais; Ricardo B Azevedo; Zulmira G M Lacava
Journal:  Int J Nanomedicine       Date:  2012-10-04

Review 2.  Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications.

Authors:  Ramya Ranganathan; Shruthilaya Madanmohan; Akila Kesavan; Ganga Baskar; Yoganathan Ramia Krishnamoorthy; Roy Santosham; D Ponraju; Suresh Kumar Rayala; Ganesh Venkatraman
Journal:  Int J Nanomedicine       Date:  2012-02-23

3.  Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles.

Authors:  Barbara Colzani; Laura Pandolfi; Ada Hoti; Pietro Alessandro Iovene; Antonino Natalello; Svetlana Avvakumova; Miriam Colombo; Davide Prosperi
Journal:  Int J Nanomedicine       Date:  2018-02-14

4.  Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies.

Authors:  Yu-Ling Lin; Nu-Man Tsai; Chia-Hung Chen; Yen-Ku Liu; Chung-Jen Lee; Yi-Lin Chan; Yu-Shan Wang; Yuan-Ching Chang; Chi-Hsin Lin; Tse-Hung Huang; Chao Ching Wang; Kwan-Hwa Chi; Kuang-Wen Liao
Journal:  J Nanobiotechnology       Date:  2019-02-06       Impact factor: 10.435

5.  Does conjugation strategy matter? Cetuximab-conjugated gold nanocages for targeting triple-negative breast cancer cells.

Authors:  S Avvakumova; L Pandolfi; E Soprano; L Moretto; M Bellini; E Galbiati; M A Rizzuto; M Colombo; R Allevi; F Corsi; A Sánchez Iglesias; D Prosperi
Journal:  Nanoscale Adv       Date:  2019-07-23

6.  Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media.

Authors:  Silvia Sommaruga; Elisabetta Galbiati; Jesus Peñaranda-Avila; Chiara Brambilla; Paolo Tortora; Miriam Colombo; Davide Prosperi
Journal:  BMC Biotechnol       Date:  2014-09-05       Impact factor: 2.563
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.