Literature DB >> 20877825

Continuous-flow synthesis of vitamin D3.

Shinichiro Fuse1, Nobutake Tanabe, Masahito Yoshida, Hayato Yoshida, Takayuki Doi, Takashi Takahashi.   

Abstract

A highly efficient, two-stage, continuous-flow synthesis of vitamin D(3) from provitamin D(3) was achieved. The developed method afforded the desired product in high yield (HPLC-UV: 60%, isolated: 32%) and required neither intermediate purification nor high-dilution conditions.

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Year:  2010        PMID: 20877825     DOI: 10.1039/c0cc02239j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  6 in total

1.  Microphotochemistry: 4,4'-Dimethoxybenzophenone mediated photodecarboxylation reactions involving phthalimides.

Authors:  Oksana Shvydkiv; Kieran Nolan; Michael Oelgemöller
Journal:  Beilstein J Org Chem       Date:  2011-08-02       Impact factor: 2.883

2.  Continuous flow photolysis of aryl azides: Preparation of 3H-azepinones.

Authors:  Farhan R Bou-Hamdan; François Lévesque; Alexander G O'Brien; Peter H Seeberger
Journal:  Beilstein J Org Chem       Date:  2011-08-17       Impact factor: 2.883

3.  Efficient amide bond formation through a rapid and strong activation of carboxylic acids in a microflow reactor.

Authors:  Shinichiro Fuse; Yuto Mifune; Takashi Takahashi
Journal:  Angew Chem Int Ed Engl       Date:  2013-12-02       Impact factor: 15.336

4.  Flow photochemistry: Old light through new windows.

Authors:  Jonathan P Knowles; Luke D Elliott; Kevin I Booker-Milburn
Journal:  Beilstein J Org Chem       Date:  2012-11-21       Impact factor: 2.883

5.  Micro-flow synthesis and structural analysis of sterically crowded diimine ligands with five aryl rings.

Authors:  Shinichiro Fuse; Nobutake Tanabe; Akio Tannna; Yohei Konishi; Takashi Takahashi
Journal:  Beilstein J Org Chem       Date:  2013-11-01       Impact factor: 2.883

Review 6.  Continuous Flow Photochemistry for the Preparation of Bioactive Molecules.

Authors:  Mara Di Filippo; Cormac Bracken; Marcus Baumann
Journal:  Molecules       Date:  2020-01-15       Impact factor: 4.411

  6 in total

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