BACKGROUND: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor. Its incidence is markedly greater in immunocompromised patients. MCC is found almost exclusively on sun-exposed facial sites. CASE REPORT: We describe a case of a 62-year-old male renal transplant recipient who was diagnosed with MCC with primary atypical localization on the buttock 5 years after transplantation. Despite the conversion from CsA to mTOR inhibitor, surgical operation, and radiotherapy, the patient developed disseminated skin lesions and died due to multiple metastases. CONCLUSIONS: This case emphasizes the importance of screening for MCC in atypical localizations in transplant organ recipients.
BACKGROUND:Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumor. Its incidence is markedly greater in immunocompromised patients. MCC is found almost exclusively on sun-exposed facial sites. CASE REPORT: We describe a case of a 62-year-old male renal transplant recipient who was diagnosed with MCC with primary atypical localization on the buttock 5 years after transplantation. Despite the conversion from CsA to mTOR inhibitor, surgical operation, and radiotherapy, the patient developed disseminated skin lesions and died due to multiple metastases. CONCLUSIONS: This case emphasizes the importance of screening for MCC in atypical localizations in transplant organ recipients.