Literature DB >> 20876493

The future of stroke imaging: what we need and how to get to it.

Carlos Leiva-Salinas1, Max Wintermark.   

Abstract

Clinical trials of reperfusion therapies for acute ischemic stroke patients in an extended time window have shown mixed results. Advanced neuroimaging for stroke, more specifically vascular imaging and perfusion/penumbral imaging, have been hypothesized to be powerful selection tools in this setting. However, a number of improvements and validation steps are needed to make these imaging techniques operational and accurate in the stroke community in general. This article briefly describes the needs in this field and recommends future steps to achieve them.

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Year:  2010        PMID: 20876493      PMCID: PMC3302851          DOI: 10.1161/STROKEAHA.110.595116

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  9 in total

Review 1.  Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: technical implementations.

Authors:  A A Konstas; G V Goldmakher; T-Y Lee; M H Lev
Journal:  AJNR Am J Neuroradiol       Date:  2009-03-19       Impact factor: 3.825

Review 2.  Optimization of perfusion imaging for acute cerebral ischemia: review of recent clinical trials and recommendations for future studies.

Authors:  James M Provenzale; Max Wintermark
Journal:  AJR Am J Roentgenol       Date:  2008-10       Impact factor: 3.959

3.  Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study.

Authors:  Gregory W Albers; Vincent N Thijs; Lawrence Wechsler; Stephanie Kemp; Gottfried Schlaug; Elaine Skalabrin; Roland Bammer; Wataru Kakuda; Maarten G Lansberg; Ashfaq Shuaib; William Coplin; Scott Hamilton; Michael Moseley; Michael P Marks
Journal:  Ann Neurol       Date:  2006-11       Impact factor: 10.422

4.  Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset.

Authors:  Anthony J Furlan; Dirk Eyding; Gregory W Albers; Yasir Al-Rawi; Kennedy R Lees; Howard A Rowley; Christian Sachara; Mariola Soehngen; Steven Warach; Werner Hacke
Journal:  Stroke       Date:  2006-03-30       Impact factor: 7.914

5.  The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase.

Authors:  Werner Hacke; Greg Albers; Yasir Al-Rawi; Julien Bogousslavsky; Antonio Davalos; Michael Eliasziw; Michael Fischer; Anthony Furlan; Markku Kaste; Kennedy R Lees; Mariola Soehngen; Steven Warach
Journal:  Stroke       Date:  2004-11-29       Impact factor: 7.914

6.  Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.

Authors:  Stephen M Davis; Geoffrey A Donnan; Mark W Parsons; Christopher Levi; Kenneth S Butcher; Andre Peeters; P Alan Barber; Christopher Bladin; Deidre A De Silva; Graham Byrnes; Jonathan B Chalk; John N Fink; Thomas E Kimber; David Schultz; Peter J Hand; Judith Frayne; Graeme Hankey; Keith Muir; Richard Gerraty; Brian M Tress; Patricia M Desmond
Journal:  Lancet Neurol       Date:  2008-02-28       Impact factor: 44.182

7.  Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study.

Authors:  Werner Hacke; Anthony J Furlan; Yasir Al-Rawi; Antoni Davalos; Jochen B Fiebach; Franz Gruber; Markku Kaste; Leslie J Lipka; Salvador Pedraza; Peter A Ringleb; Howard A Rowley; Dietmar Schneider; Lee H Schwamm; Joaquin Serena Leal; Mariola Söhngen; Phil A Teal; Karin Wilhelm-Ogunbiyi; Max Wintermark; Steven Warach
Journal:  Lancet Neurol       Date:  2008-12-25       Impact factor: 44.182

8.  Acute stroke imaging research roadmap.

Authors:  Max Wintermark; Gregory W Albers; Andrei V Alexandrov; Jeffry R Alger; Roland Bammer; Jean-Claude Baron; Stephen Davis; Bart M Demaerschalk; Colin P Derdeyn; Geoffrey A Donnan; James D Eastwood; Jochen B Fiebach; Marc Fisher; Karen L Furie; Gregory V Goldmakher; Werner Hacke; Chelsea S Kidwell; Stephan P Kloska; Martin Köhrmann; Walter Koroshetz; Ting-Yim Lee; Kennedy R Lees; Michael H Lev; David S Liebeskind; Leif Ostergaard; William J Powers; James Provenzale; Peter Schellinger; Robert Silbergleit; Alma Gregory Sorensen; Joanna Wardlaw; Ona Wu; Steven Warach
Journal:  AJNR Am J Neuroradiol       Date:  2008-05       Impact factor: 3.825

9.  FDA investigates the safety of brain perfusion CT.

Authors:  M Wintermark; M H Lev
Journal:  AJNR Am J Neuroradiol       Date:  2009-11-05       Impact factor: 4.966

  9 in total
  4 in total

1.  Standardization of Stroke Perfusion CT for Reperfusion Therapy.

Authors:  Guangming Zhu; Patrik Michel; Weiwei Zhang; Max Wintermark
Journal:  Transl Stroke Res       Date:  2012-03-28       Impact factor: 6.829

2.  Utilization of Emergent Neuroimaging for Thrombolysis-Eligible Stroke Patients.

Authors:  Nerses Sanossian; Katherine A Fu; David S Liebeskind; Sidney Starkman; Scott Hamilton; J Pablo Villablanca; Adrian M Burgos; Robin Conwit; Jeffrey L Saver
Journal:  J Neuroimaging       Date:  2016-06-14       Impact factor: 2.486

3.  A concerted appeal for international cooperation in preclinical stroke research.

Authors:  Ulrich Dirnagl; Antoine Hakim; Malcolm Macleod; Marc Fisher; David Howells; Stuart M Alan; Gary Steinberg; Anna Planas; Johannes Boltze; Sean Savitz; Costantino Iadecola; Stephen Meairs
Journal:  Stroke       Date:  2013-04-18       Impact factor: 7.914

4.  Can Dynamic Contrast-Enhanced CT Quantify Perfusion in a Stimulated Muscle of Limited Size? A Rat Model.

Authors:  John A Walker; Thomas J Walters; Matthew D Parker; Joseph C Wenke
Journal:  Clin Orthop Relat Res       Date:  2020-01       Impact factor: 4.755

  4 in total

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