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Literature DB >> 20876486

Targets for neural repair therapies after stroke.

Abstract

Studies of neural repair after stroke have developed from a relatively small number of laboratories doing highly creative discovery science to a field in which reproducible evidence supports distinct pathways, processes, and molecules that promote recovery. This review focuses on some emerging targets for neural repair or recovery in stroke and on their limitations.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 20876486 PMCID： PMC2955885 DOI： 10.1161/STROKEAHA.110.597146

Source DB: PubMed Journal: Stroke ISSN： 0039-2499 Impact factor: 7.914

38 in total

Review 1. Cellular and molecular mechanisms of neural repair after stroke: making waves.

Authors: S Thomas Carmichael
Journal: Ann Neurol Date: 2006-05 Impact factor: 10.422

2. Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

Authors: Caroline Gregorian; Jonathan Nakashima; Janel Le Belle; John Ohab; Rachel Kim; Annie Liu; Kate Barzan Smith; Matthias Groszer; A Denise Garcia; Michael V Sofroniew; S Thomas Carmichael; Harley I Kornblum; Xin Liu; Hong Wu
Journal: J Neurosci Date: 2009-02-11 Impact factor: 6.167

3. LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury.

Authors: Benxiu Ji; Mingwei Li; Wu-Tian Wu; Leung-Wah Yick; Xinhua Lee; Zhaohui Shao; Joy Wang; Kwok-Fai So; John M McCoy; R Blake Pepinsky; Sha Mi; Jane K Relton
Journal: Mol Cell Neurosci Date: 2006-09-29 Impact factor: 4.314

4. Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.

Authors: Philip Duffy; Andre Schmandke; Antonio Schmandke; Jonathan Sigworth; Shuh Narumiya; William B J Cafferty; Stephen M Strittmatter
Journal: J Neurosci Date: 2009-12-02 Impact factor: 6.167

5. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.

Authors: Yingjie Shen; Alan P Tenney; Sarah A Busch; Kevin P Horn; Fernando X Cuascut; Kai Liu; Zhigang He; Jerry Silver; John G Flanagan
Journal: Science Date: 2009-10-15 Impact factor: 47.728

6. A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway.

Authors: Thong C Ma; Aline Campana; Philipp S Lange; Hsin-Hwa Lee; Kasturi Banerjee; J Barney Bryson; Lata Mahishi; Shabnam Alam; Roman J Giger; Stephen Barnes; Sidney M Morris; Dianna E Willis; Jeffrey L Twiss; Marie T Filbin; Rajiv R Ratan
Journal: J Neurosci Date: 2010-01-13 Impact factor: 6.167

7. Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury.

Authors: Tomohiro Miyashita; Masao Koda; Keiko Kitajo; Masashi Yamazaki; Kazuhisa Takahashi; Akira Kikuchi; Toshihide Yamashita
Journal: J Neurotrauma Date: 2009-07 Impact factor: 5.269

8. Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

Authors: H Tanaka; T Yamashita; K Yachi; T Fujiwara; H Yoshikawa; M Tohyama
Journal: Neuroscience Date: 2004 Impact factor: 3.590

9. Involvement of Sema4D in the control of microglia activation.

Authors: Marcia Toguchi; Daniel Gonzalez; Sohei Furukawa; Shinobu Inagaki
Journal: Neurochem Int Date: 2009-05-23 Impact factor: 3.921

10. Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

Authors: Shuxin Li; Betty P Liu; Stephane Budel; Mingwei Li; Benxiu Ji; Lee Walus; Weiwei Li; Adrienna Jirik; Sylvia Rabacchi; Eugene Choi; Dane Worley; Dinah W Y Sah; Blake Pepinsky; Daniel Lee; Jane Relton; Stephen M Strittmatter
Journal: J Neurosci Date: 2004-11-17 Impact factor: 6.167

14 in total

1. Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke.

Authors: Jullet Han; Julia Pollak; Tao Yang; Mohammad R Siddiqui; Kristian P Doyle; Kereshmeh Taravosh-Lahn; Egle Cekanaviciute; Alex Han; Jeremy Z Goodman; Britta Jones; Deqiang Jing; Stephen M Massa; Frank M Longo; Marion S Buckwalter
Journal: Stroke Date: 2012-04-24 Impact factor: 7.914

Review 2. Functional recovery following motor cortex lesions in non-human primates: experimental implications for human stroke patients.

Authors: Warren G Darling; Marc A Pizzimenti; Robert J Morecraft
Journal: J Integr Neurosci Date: 2011-09 Impact factor: 2.117

Targets for neural repair therapies after stroke.

Review 1. Cellular and molecular mechanisms of neural repair after stroke: making waves.

2. Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

3. LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury.

4. Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.

5. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.

6. A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway.

7. Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury.

8. Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

9. Involvement of Sema4D in the control of microglia activation.

10. Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

1. Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke.

Review 2. Functional recovery following motor cortex lesions in non-human primates: experimental implications for human stroke patients.

3. Memantine enhances recovery from stroke.

4. Neuronal production of lipocalin-2 as a help-me signal for glial activation.

Review 5. The role of astrocytes in mediating exogenous cell-based restorative therapy for stroke.

Review 6. Meningeal Multipotent Cells: A Hidden Target for CNS Repair?

7. Combining BMI Stimulation and Mathematical Modeling for Acute Stroke Recovery and Neural Repair.

8. Perisynaptic GABA Receptors The Overzealous Protector.

Review 9. Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke.

Review 10. Noninvasive strategies to promote functional recovery after stroke.