Literature DB >> 20872944

The use of allograft shell with intramedullary vascularized fibula graft for intercalary reconstruction after diaphyseal resection for lower extremity bony malignancy.

Jing Li1, Zhen Wang, Zheng Guo, Guo-Jing Chen, Jun Fu, Guo-Xian Pei.   

Abstract

BACKGROUND: Reconstruction after excision of the femur and tibia malignancy is a challenging issue for the reconstructive surgeon. The combined use of a vascularized fibular flap and allograft can provide a reliable reconstructive option. This article describes the authors' experience with this technique for the treatment of large-segmental bone defects after intercalary resection of lower extremity malignancy.
METHODS: From 2003 to 2008, 11 patients that had intercalary resection of lower extremity malignancy underwent reconstruction with an allograft and vascularized fibular construct. Time to union was recorded through evaluation of plain radiographs. Patients were examined clinically and radiographically and were assessed functionally with MSTS score. RESULT: The average age at time of operation was 18.5 years. The mean follow-up time was 34.1 months. The oncology result was continuous disease free in 7 patients, no evidence of disease in 2, alive with disease in 1, and died of disease in 1. Free vascularized fibula flap was used in 7 patients and ispilateral pedicle vascularized fibula in 4. The average length of the resected segment was 12.1 cm and that of the fibula flap was 16.2 cm. The primary unions were achieved in all patients except one with tibia reconstruction. The average time for bone union was 5.4 months at fibula-host junction and 11.8 months at allograft-host junction. There were no allograft fractures and no infections. Five patients had 7 local complications. The MSTS average score was 91.8% at final follow-up. The mean time of weight-bearing was 12.4 months.
CONCLUSIONS: Intramedullary fibular flap in combination with massive allografts provide an excellent option for reconstruction of large-bony defects after lower extremity malignancy extirpation. The viability of the fibula is a cornerstone in success of reconstruction that prevents allograft nonunion and result in decreased time to bone healing, leading to earlier patient recovery and return of function. J. Surg. Oncol. 2010;102:368-374.
© 2010 Wiley-Liss, Inc.

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Year:  2010        PMID: 20872944     DOI: 10.1002/jso.21620

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  16 in total

Review 1.  Intercalary reconstructions after bone tumor resections: a review of treatments.

Authors:  Georgios N Panagopoulos; Andreas F Mavrogenis; Cyril Mauffrey; Jan Lesenský; Andrea Angelini; Panayiotis D Megaloikonomos; Vasilios G Igoumenou; John Papanastassiou; Olga Savvidou; Pietro Ruggieri; Panayiotis J Papagelopoulos
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-06-05

Review 2.  Treatment of critical-sized bone defects: clinical and tissue engineering perspectives.

Authors:  Erika Roddy; Malcolm R DeBaun; Adam Daoud-Gray; Yunzhi P Yang; Michael J Gardner
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-10-28

3.  An Injectable Hydrogel as Bone Graft Material with Added Antimicrobial Properties.

Authors:  Giacomo Tommasi; Stefano Perni; Polina Prokopovich
Journal:  Tissue Eng Part A       Date:  2016-06-01       Impact factor: 3.845

4.  Is There Benefit to Free Over Pedicled Vascularized Grafts in Augmenting Tibial Intercalary Allograft Constructs?

Authors:  Marco Manfrini; Srimanth Bindiganavile; Ferhat Say; Marco Colangeli; Laura Campanacci; Massimiliano Depaolis; Massimo Ceruso; Davide Donati
Journal:  Clin Orthop Relat Res       Date:  2016-12-19       Impact factor: 4.176

5.  Lower Limb Reconstruction Using Tibial Strut Autograft after Resection of Primary Malignant Bone Tumors in Skeletally Immature Patients.

Authors:  Bassem I Haddad; Mohammed S Alisi; Mohamad S Yasin; Mohammad Q Hamdan; Freih O Abu Hassan Frcs
Journal:  Arch Bone Jt Surg       Date:  2021-09

Review 6.  Vascularized fibular grafts for the treatment of long bone defects: pros and cons. A systematic review and meta-analysis.

Authors:  Christian Candrian; Giuseppe Filardo; Pietro Feltri; Luca Solaro; Costantino Errani; Guglielmo Schiavon
Journal:  Arch Orthop Trauma Surg       Date:  2021-06-10       Impact factor: 3.067

Review 7.  Vascularized Bone Grafts in Spinal Reconstruction: An Overview of Nomenclature and Indications.

Authors:  Anna J Skochdopole; Ryan D Wagner; Matthew J Davis; Sarth Raj; Sebastian J Winocour; Alexander E Ropper; David S Xu; Michael A Bohl; Edward M Reece
Journal:  Semin Plast Surg       Date:  2021-05-10       Impact factor: 2.314

8.  Does the Addition of a Vascularized Fibula Improve the Results of a Massive Bone Allograft Alone for Intercalary Femur Reconstruction of Malignant Bone Tumors in Children?

Authors:  Costantino Errani; Patricio A Alfaro; Virginia Ponz; Marco Colangeli; Davide Maria Donati; Marco Manfrini
Journal:  Clin Orthop Relat Res       Date:  2021-06-01       Impact factor: 4.755

9.  Intercalary reconstructions with vascularised fibula and allograft after tumour resection in the lower limb.

Authors:  Katharina Rabitsch; Werner Maurer-Ertl; Ulrike Pirker-Frühauf; Christine Wibmer; Andreas Leithner
Journal:  Sarcoma       Date:  2013-05-23

10.  Intercalary reconstruction following resection of diaphyseal bone tumors: A systematic review.

Authors:  Costantino Errani; Shinji Tsukamoto; Nusaibah Almunhaisen; Andreas Mavrogenis; Davide Donati
Journal:  J Clin Orthop Trauma       Date:  2021-05-07
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