BACKGROUND: Anastomotic leakage (AL) is the most feared complication of colorectal surgery. Atherosclerosis is suggested to have a detrimental effect on anastomotic healing. This study aimed to analyze the calcium score, a measure for atherosclerosis, as a risk factor for AL. STUDY DESIGN: The calcium scores of colorectal patients operated on in 2 Dutch university medical centers were determined using a computed tomography scan and calcium scoring software. The aorta, common iliac arteries, internal and external iliac arteries were studied. Additionally, patient- and operation-related factors were scored. RESULTS: A total of 122 patients were included. In patients with AL, calcium scores were significantly higher in the left common iliac artery (561.4 vs 156.0, P = .028), right common iliac artery (542.0 vs 144.4, P = .041), both common iliac arteries together (1,103.3 vs 301.9, P = .046), and the left internal iliac artery (716.3 vs 35.3, P = .044). CONCLUSIONS: Patients with higher calcium scores in the iliacal arteries have an increased leakage risk.
BACKGROUND: Anastomotic leakage (AL) is the most feared complication of colorectal surgery. Atherosclerosis is suggested to have a detrimental effect on anastomotic healing. This study aimed to analyze the calcium score, a measure for atherosclerosis, as a risk factor for AL. STUDY DESIGN: The calcium scores of colorectalpatients operated on in 2 Dutch university medical centers were determined using a computed tomography scan and calcium scoring software. The aorta, common iliac arteries, internal and external iliac arteries were studied. Additionally, patient- and operation-related factors were scored. RESULTS: A total of 122 patients were included. In patients with AL, calcium scores were significantly higher in the left common iliac artery (561.4 vs 156.0, P = .028), right common iliac artery (542.0 vs 144.4, P = .041), both common iliac arteries together (1,103.3 vs 301.9, P = .046), and the left internal iliac artery (716.3 vs 35.3, P = .044). CONCLUSIONS:Patients with higher calcium scores in the iliacal arteries have an increased leakage risk.
Authors: Verena N N Kornmann; Nikki Treskes; Lilian H F Hoonhout; Thomas L Bollen; Bert van Ramshorst; Djamila Boerma Journal: Int J Colorectal Dis Date: 2012-12-14 Impact factor: 2.571
Authors: Katrina A Knight; Chui Hon Fei; Kate F Boland; Daniel R Dolan; Allan M Golder; Donald C McMillan; Paul G Horgan; Douglas H Black; James H Park; Campbell S D Roxburgh Journal: Eur Radiol Date: 2020-11-17 Impact factor: 5.315
Authors: Verena N N Kornmann; Michiel H van Werkum; Thomas L Bollen; Bert van Ramshorst; Djamila Boerma Journal: Surg Today Date: 2013-10-01 Impact factor: 2.549
Authors: Benjamin J Jefferies; Emily Evans; James Bundred; James Hodson; John L Whiting; Colm Forde; Ewen A Griffiths Journal: World J Gastrointest Surg Date: 2019-07-27
Authors: Audrey Chm Jongen; Joanna Wam Bosmans; Serdar Kartal; Tim Lubbers; Meindert Sosef; Gerrit D Slooter; Jan H Stoot; Frederik-Jan van Schooten; Nicole D Bouvy; Joep Pm Derikx Journal: JMIR Res Protoc Date: 2016-06-09
Authors: Ruben V C Buijs; Eva L Leemans; Marcel Greuter; Ignace F J Tielliu; Clark J Zeebregts; Tineke P Willems Journal: PLoS One Date: 2018-02-28 Impact factor: 3.240