Literature DB >> 20866572

Extended narrow escape problem: boundary homogenization-based analysis.

A M Berezhkovskii1, A V Barzykin.   

Abstract

Diffusion of particles in confined domains with absorbing spots on the otherwise reflecting boundaries is ubiquitous in nature and technology. Because of nonuniform boundary conditions, the problem of finding the mean first passage time (MFPT) of the particle to one of the spots is extremely complicated. We show how the difficulties can be overcome by means of boundary homogenization when the domain is a circular disk whose boundary contains n nonoverlapping identical absorbing arcs, which may occupy an arbitrary fraction of the boundary. We find the MFPT as a function of the fraction of the boundary occupied by the arcs (i) for n evenly spaced arcs and (ii) for two arcs arbitrarily located on the boundary. As the arc length tends to zero, our approximate solution reduces to the known asymptotic formula for the MFPT rigorously derived in studies devoted of the narrow escape problem.

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Year:  2010        PMID: 20866572      PMCID: PMC4955386          DOI: 10.1103/PhysRevE.82.011114

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  18 in total

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2.  Kinetics of ligand equilibration between tubular and vesicular parts of the endosome.

Authors:  Leonardo Dagdug; Alexander M Berezhkovskii; George H Weiss
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3.  Boundary homogenization for trapping by patchy surfaces.

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Journal:  J Chem Phys       Date:  2004-12-08       Impact factor: 3.488

4.  Ligand accumulation in autocrine cell cultures.

Authors:  Michael I Monine; Alexander M Berezhkovskii; Elizabeth J Joslin; H Steven Wiley; Douglas A Lauffenburger; Stanislav Y Shvartsman
Journal:  Biophys J       Date:  2005-01-14       Impact factor: 4.033

5.  Homogenization of boundary conditions for surfaces with regular arrays of traps.

Authors:  Alexander M Berezhkovskii; Michael I Monine; Cyrill B Muratov; Stanislav Y Shvartsman
Journal:  J Chem Phys       Date:  2006-01-21       Impact factor: 3.488

6.  Diffusion model of solute dynamics in a membrane channel: mapping onto the two-site model and optimizing the flux.

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7.  First-passage times for random walks in bounded domains.

Authors:  S Condamin; O Bénichou; M Moreau
Journal:  Phys Rev Lett       Date:  2005-12-19       Impact factor: 9.161

8.  One-dimensional description of diffusion in a tube of abruptly changing diameter: Boundary homogenization based approach.

Authors:  Alexander M Berezhkovskii; Alexander V Barzykin; Vladimir Yu Zitserman
Journal:  J Chem Phys       Date:  2009-12-14       Impact factor: 3.488

9.  Narrow-escape time problem: time needed for a particle to exit a confining domain through a small window.

Authors:  O Bénichou; R Voituriez
Journal:  Phys Rev Lett       Date:  2008-04-23       Impact factor: 9.161

10.  Diffusion in narrow domains and application to phototransduction.

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Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2009-03-17
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  2 in total

1.  Diffusion in periodic two-dimensional channels formed by overlapping circles: comparison of analytical and numerical results.

Authors:  Inti Pineda; Marco-Vinicio Vazquez; Alexander M Berezhkovskii; Leonardo Dagdug
Journal:  J Chem Phys       Date:  2011-12-14       Impact factor: 3.488

2.  Trapping of diffusing particles by striped cylindrical surfaces. Boundary homogenization approach.

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Journal:  J Chem Phys       Date:  2015-06-21       Impact factor: 3.488

  2 in total

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