Literature DB >> 20865465

Survival after diphenhydramine ingestion with hemodialysis in a toddler.

Nathanael J McKeown1, Patrick L West, Robert G Hendrickson, B Zane Horowitz.   

Abstract

A 13-month-old male who ingested 20 diphenhydramine (25 mg) tablets presented with seizures and ultimately progressed to status epilepticus and wide-complex tachycardia. Due to worsening clinical course, hemodialysis was performed with temporal resolution of his symptoms. Hemodialysis may be considered in critically ill diphenhydramine overdoses not responsive to conventional supportive care.

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Year:  2011        PMID: 20865465      PMCID: PMC3724430          DOI: 10.1007/s13181-010-0116-4

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  11 in total

1.  DIPHENHYDRAMINE POISONING TREATED BY EXCHANGE TRANSFUSION.

Authors:  R F HUXTABLE; J LANDWIRTH
Journal:  Am J Dis Child       Date:  1963-11

2.  Life-threatening diphenhydramine overdose treated with charcoal hemoperfusion and hemodialysis.

Authors:  M E Mullins; R V Pinnick; J M Terhes
Journal:  Ann Emerg Med       Date:  1999-01       Impact factor: 5.721

3.  Dose-dependent toxicity of diphenhydramine overdose.

Authors:  D Radovanovic; P J Meier; M Guirguis; J P Lorent; H Kupferschmidt
Journal:  Hum Exp Toxicol       Date:  2000-09       Impact factor: 2.903

4.  Hemodialysis in poisoning with methaqualone and diphenydramine.

Authors:  D T Caridis; G M McAndrew; N A Matheson
Journal:  Lancet       Date:  1967-01-07       Impact factor: 79.321

5.  Recovery after massive overdose of diphenhydramine and methaqualone.

Authors:  M R Wallace; E Allen
Journal:  Lancet       Date:  1968-12-07       Impact factor: 79.321

6.  Diphenhydramine: pharmacokinetics and pharmacodynamics in elderly adults, young adults, and children.

Authors:  K J Simons; W T Watson; T J Martin; X Y Chen; F E Simons
Journal:  J Clin Pharmacol       Date:  1990-07       Impact factor: 3.126

Review 7.  Fatality from diphenhydramine monointoxication: a case report and review of the infant, pediatric, and adult literature.

Authors:  Jeffrey S Nine; Chad R Rund
Journal:  Am J Forensic Med Pathol       Date:  2006-03       Impact factor: 0.921

8.  2008 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 26th Annual Report.

Authors:  Alvin C Bronstein; Daniel A Spyker; Louis R Cantilena; Jody L Green; Barry H Rumack; Sandra L Giffin
Journal:  Clin Toxicol (Phila)       Date:  2009-12       Impact factor: 4.467

9.  Clinical symptomatology of diphenhydramine overdose: an evaluation of 136 cases in 1982 to 1985.

Authors:  C Köppel; K Ibe; J Tenczer
Journal:  J Toxicol Clin Toxicol       Date:  1987

10.  Massive diphenhydramine overdose resulting in death.

Authors:  E P Krenzelok; G M Anderson; M Mirick
Journal:  Ann Emerg Med       Date:  1982-04       Impact factor: 5.721

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