BACKGROUND: QT interval variability provides information on ventricular vulnerability. However, QT interval variability in children has not been adequately evaluated. METHODS: One hundred seventy-three consecutive nursing infants and children (male-female, 106:67) up to school age with no intrinsic cardiac disease were included in this study, and they were categorized into 6 age-related groups. The QT variability index (QTVI) was calculated based on an electrocardiogram; and age-specific standard values, sex-specific classification, and a standard growth curve covering 0 to 7 years were constructed. RESULTS: The QTVI decreased in an age-dependent manner, reached constant values after school age, and exhibited no sex-specific differences in 6 age-related groups. CONCLUSIONS: Based on the age-dependent standardized QTVI values, it is possible to estimate the instability of ventricular repolarization in pediatric patients with better accuracy.
BACKGROUND: QT interval variability provides information on ventricular vulnerability. However, QT interval variability in children has not been adequately evaluated. METHODS: One hundred seventy-three consecutive nursing infants and children (male-female, 106:67) up to school age with no intrinsic cardiac disease were included in this study, and they were categorized into 6 age-related groups. The QT variability index (QTVI) was calculated based on an electrocardiogram; and age-specific standard values, sex-specific classification, and a standard growth curve covering 0 to 7 years were constructed. RESULTS: The QTVI decreased in an age-dependent manner, reached constant values after school age, and exhibited no sex-specific differences in 6 age-related groups. CONCLUSIONS: Based on the age-dependent standardized QTVI values, it is possible to estimate the instability of ventricular repolarization in pediatric patients with better accuracy.
Authors: Mathias Baumert; Alberto Porta; Marc A Vos; Marek Malik; Jean-Philippe Couderc; Pablo Laguna; Gianfranco Piccirillo; Godfrey L Smith; Larisa G Tereshchenko; Paul G A Volders Journal: Europace Date: 2016-01-27 Impact factor: 5.214
Authors: Marten E van den Berg; Jan A Kors; Gerard van Herpen; Michiel L Bots; Hans Hillege; Cees A Swenne; Bruno H Stricker; Peter R Rijnbeek Journal: Front Physiol Date: 2019-10-04 Impact factor: 4.566