Literature DB >> 20863222

A case of acetaminophen (paracetamol) causing renal failure without liver damage in a child and review of literature.

Ozan Ozkaya1, Gurkan Genc, Kenan Bek, Yurdanur Sullu.   

Abstract

Acetaminophen (paracetamol) is a widely used drug and known as a safety antipyretic and analgesic drug in childhood. Acetaminophen-associated liver damage is more recognized than kidney damage. Nephrotoxicity and hepatotoxicity can be seen together after acetaminophen overdose, but renal damage without liver damage is a rarely seen entity in all age groups being reported more rarely in childhood. We present here a 16-year-old girl with renal failure without liver damage because of acetaminophen toxicity and a review of literature for pathophysiological mechanisms, clinical course, treatment, and outcome.

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Year:  2010        PMID: 20863222     DOI: 10.3109/0886022X.2010.509830

Source DB:  PubMed          Journal:  Ren Fail        ISSN: 0886-022X            Impact factor:   2.606


  5 in total

1.  A case of acetaminophen-induced acute tubulointerstitial nephritis in adult.

Authors:  Dan Inoue; Ryosuke Usui; Kosaku Nitta; Minako Koike
Journal:  CEN Case Rep       Date:  2017-08-11

2.  Risk factors and outcomes of acute kidney injury in patients with acute liver failure.

Authors:  Shannan R Tujios; Linda S Hynan; Miguel A Vazquez; Anne M Larson; Emmanuel Seremba; Corron M Sanders; William M Lee
Journal:  Clin Gastroenterol Hepatol       Date:  2014-07-11       Impact factor: 11.382

3.  4-methylpyrazole protects against acetaminophen-induced acute kidney injury.

Authors:  Jephte Y Akakpo; Anup Ramachandran; Hilmi Orhan; Steven C Curry; Barry H Rumack; Hartmut Jaeschke
Journal:  Toxicol Appl Pharmacol       Date:  2020-11-04       Impact factor: 4.219

Review 4.  Fighting Oxidative Stress with Sulfur: Hydrogen Sulfide in the Renal and Cardiovascular Systems.

Authors:  Joshua J Scammahorn; Isabel T N Nguyen; Eelke M Bos; Harry Van Goor; Jaap A Joles
Journal:  Antioxidants (Basel)       Date:  2021-03-02

5.  Acute Renal Impairment in Patients Due to Paracetamol Overdose in the Absence of Hepatic Impairment.

Authors:  Zahid Khan; Mohammed Abumedian; Mildred Ibekwe; Khalid Musa; Gideon Mlawa
Journal:  Cureus       Date:  2021-12-27
  5 in total

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