Alon Nevet1, Shai Ashkenazi, Zmira Samra, Gilat Livni. 1. Department of Pediatrics A, Schneider Children's Medical Center Petah Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Abstract
BACKGROUND: Community-associated methicillin-resistant Staphylococcus aureus infections are increasingly being documented worldwide. In Israel, however, CA-MRSA infections have not yet been reported, so awareness among physicians may be low. OBJECTIVE: To alert physicians to the possibility of CA-MRSA infection, which necessitates a distinct therapeutic approach. METHODS: We present three children with soft tissue infections caused by CA-MRSA who were treated in our medical center from January to March 2009. RESULTS: In all three cases CA-MRSA was identified as the causative pathogen after surgical or spontaneous drainage. On susceptibility testing, the organisms were resistant to beta-lactam antibiotics but susceptible to clindamycin, rifampicin and trimethoprim-sulfamethoxazole. CONCLUSIONS: Physicians should maintain an index of suspicion for CA-MRSA infections. The antibiotic-resistance profile of S. aureus should be watched carefully, and in particular, cultures should be obtained whenever soft tissue infections fail to respond to conventional treatment.
BACKGROUND: Community-associated methicillin-resistant Staphylococcus aureus infections are increasingly being documented worldwide. In Israel, however, CA-MRSA infections have not yet been reported, so awareness among physicians may be low. OBJECTIVE: To alert physicians to the possibility of CA-MRSA infection, which necessitates a distinct therapeutic approach. METHODS: We present three children with soft tissue infections caused by CA-MRSA who were treated in our medical center from January to March 2009. RESULTS: In all three cases CA-MRSA was identified as the causative pathogen after surgical or spontaneous drainage. On susceptibility testing, the organisms were resistant to beta-lactam antibiotics but susceptible to clindamycin, rifampicin and trimethoprim-sulfamethoxazole. CONCLUSIONS: Physicians should maintain an index of suspicion for CA-MRSA infections. The antibiotic-resistance profile of S. aureus should be watched carefully, and in particular, cultures should be obtained whenever soft tissue infections fail to respond to conventional treatment.
Authors: E Berla-Kerzhner; A Biber; M Parizade; D Taran; G Rahav; G Regev-Yochay; D Glikman Journal: Eur J Clin Microbiol Infect Dis Date: 2016-09-27 Impact factor: 3.267