Literature DB >> 20859314

A treatment option for post-injection sciatic neuropathy: transsacral block with methylprednisolone.

H Evren Eker1, Oya Yalcin Cok, Anis Aribogan.   

Abstract

BACKGROUND: Accidental intraneural injection induced nerve injury is an iatrogenic tragedy and intramuscular injection (IM) is the most common injury mechanism affecting the sciatic nerve. The most frequent presentation of sciatic nerve injury includes radicular pain and paresthesia with almost immediate onset of variable motor and sensory deficit.
OBJECTIVES: Intraneural injection is a common injury mechanism of the sciatic nerve and generates neuropathic pain with inflammatory neuritis. Steroids inhibit the production of inflammatory mediators and reduce ectopic discharges on damaged neural membranes. The results of transsacral steroid injection on neuropathic pain in 5 patients with accidental sciatic nerve injury due to intraneural injection were presented in this report.
DESIGN: Report of 5 cases. DESCRIPTION OF CASES: Five patients, 32, 34, 45, 54 and 70 years old respectively, complaining of severe neuropathic pain, paresthesia and progressive weakness of the lower extremity with difficulty in walking secondary to gluteal injection were admitted to the clinic. The symptoms were resistant to drug therapies. Electromyography disclosed axonal damage of the sciatic nerve. The initial examination of the patients revealed a Numeric Rating Scale (NRS) of 10, 10, 9, 9, and 10 respectively.
RESULTS: Diagnostic block was performed through the unilateral S1-S2-S3 sacral foramina with 22-G spinal needle by 5 mL 1% lidocaine into each foramen. NRS scores decreased to 1, 2, 2, 2 and 1, respectively. One week later, the patients were administered 80 mg methylprednisolone with 1% lidocaine in 15 mL solution shared equally in each foramen. The patients were checked one month after therapeutic block and a full recovery was achieved in all patients.
CONCLUSION: The neuropathic pain due to accidental intraneural injection of the sciatic nerve would be an acceptable indication for transsacral nerve block with corticosteroids in the treatment of sciatic neuropathic pain symptoms.

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Year:  2010        PMID: 20859314

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  7 in total

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Authors:  Md Abu Bakar Siddiq; Md Shawkat Hossain; Mohammad Moin Uddin; Israt Jahan; Moshiur Rahman Khasru; Neaz Mahmud Haider; Johannes J Rasker
Journal:  Eur J Orthop Surg Traumatol       Date:  2016-09-19

2.  Sciatic Nerve Intrafascicular Injection Induces Neuropathy by Activating the Matrix Modulators MMP-9 and TIMP-1.

Authors:  Kuang-Yi Tseng; Hung-Chen Wang; Kai-Feng Cheng; Yi-Hsuan Wang; Lin-Li Chang; Kuang-I Cheng
Journal:  Front Pharmacol       Date:  2022-05-20       Impact factor: 5.988

3.  Use of fluoroscopic-guided transsacral block for the treatment of iatrogenic post-injection sciatic neuropathy: Report of three cases.

Authors:  Savaş Şencan; İsa Cüce; Osman Hakan Gündüz
Journal:  Turk J Phys Med Rehabil       Date:  2019-11-22

4.  Histopathological effects of intramuscular metamizole sodium on rat sciatic nerve.

Authors:  Abdurrahman Emir; Yıldıray Kalkan; Habib Bostan
Journal:  Iran J Basic Med Sci       Date:  2016-08       Impact factor: 2.699

5.  Effects of a Short Course of Oral Prednisolone in Patients with Bladder Pain Syndrome with Fluctuating, Worsening Pain despite Low-Dose Triple Therapy.

Authors:  Hee Jong Jeong
Journal:  Int Neurourol J       Date:  2012-12-31       Impact factor: 2.835

6.  Sciatic Nerve Injection Palsy in Children, Electrophysiologic Pattern and Outcome: A Case Series Study.

Authors:  Vahideh Toopchizadeh; Mohammad Barzegar; Afshin Habibzadeh
Journal:  Iran J Child Neurol       Date:  2015

7.  The effect of popliteal sciatic nerve block with methylprednisolone in the management of post-injection sciatic neuropathy after clinical and electrophysiological examination.

Authors:  Damla Yürük; Ayçin Yildiz Tabakoğlu
Journal:  Turk J Med Sci       Date:  2021-08-09       Impact factor: 0.973

  7 in total

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