Literature DB >> 20857989

Palladium-catalyzed C-H functionalization of heteroarenes with aryl bromides and chlorides.

Shunsuke Tamba1, Youhei Okubo, Shota Tanaka, Daiki Monguchi, Atsunori Mori.   

Abstract

Palladium-catalyzed C-H arylation of electron-enriched heteroarenes with aryl bromides and aryl chlorides proceeds in the presence of LiO-t-Bu as a base. The reaction allows one-pot synthesis of differently substituted 2,5-diarylthiazole with the same catalyst system by switching the solvent and the amount of base.

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Year:  2010        PMID: 20857989     DOI: 10.1021/jo101433g

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  5 in total

1.  tBu3P-Coordinated 2-Phenylaniline-Based Palladacycle Complex As Precatalyst for Pd-Catalyzed Coupling Reactions of Aryl Halides with Polyfluoroarenes via C-H Activation Strategy.

Authors:  Hong-Hai Zhang; Jie Dong; Qiao-Sheng Hu
Journal:  European J Org Chem       Date:  2014-02-01

2.  Room-Temperature Direct β-Arylation of Thiophenes and Benzo[b]thiophenes and Kinetic Evidence for a Heck-type Pathway.

Authors:  Chiara Colletto; Saidul Islam; Francisco Juliá-Hernández; Igor Larrosa
Journal:  J Am Chem Soc       Date:  2016-01-28       Impact factor: 15.419

3.  Ag(I)-C-H Activation Enables Near-Room-Temperature Direct α-Arylation of Benzo[ b]thiophenes.

Authors:  Chiara Colletto; Adyasha Panigrahi; Jaime Fernández-Casado; Igor Larrosa
Journal:  J Am Chem Soc       Date:  2018-07-23       Impact factor: 15.419

4.  Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts: Direct arylation of heterocycles.

Authors:  Anthony R Martin; Anthony Chartoire; Alexandra M Z Slawin; Steven P Nolan
Journal:  Beilstein J Org Chem       Date:  2012-09-27       Impact factor: 2.883

5.  Direct Arylation of Benzo[b]furan and Other Benzo-Fused Heterocycles.

Authors:  Toan Dao-Huy; Maximilian Haider; Fabian Glatz; Michael Schnürch; Marko D Mihovilovic
Journal:  European J Org Chem       Date:  2014-11-17
  5 in total

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