| Literature DB >> 20857365 |
Antonia Masch1, Johannes Zerweck, Ulf Reimer, Holger Wenschuh, Mike Schutkowski.
Abstract
Circulating antibodies are highly selective binding reagents directed to a vast repertoire of antigens. Candidate antigens displayed as overlapping peptides on microarrays can be used to screen for recognition by serum antibodies from clinically well-defined patient populations. The methodology is robust and enables unbiased visualization of antigen-specific B-cell responses. Additionally, autoantibody signatures of diagnostic value could be detected using microarrays displaying thousands of human peptides.Entities:
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Year: 2010 PMID： 20857365 DOI： 10.1007/978-1-60761-845-4_13
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745