Literature DB >> 20856239

Is P-glycoprotein involved in amyloid-β elimination across the blood-brain barrier in Alzheimer's disease?

S Ohtsuki1, S Ito, T Terasaki.   

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Year:  2010        PMID： 20856239     DOI： 10.1038/clpt.2010.160

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


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  7 in total

1.  Evaluation of [18F]MC225 as a PET radiotracer for measuring P-glycoprotein function at the blood-brain barrier in rats: Kinetics, metabolism, and selectivity.

Authors:  Heli Savolainen; Albert D Windhorst; Philip H Elsinga; Mariangela Cantore; Nicola A Colabufo; Antoon Tm Willemsen; Gert Luurtsema
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

2.  P-glycoprotein Function in the Rodent Brain Displays a Daily Rhythm, a Quantitative In Vivo PET Study.

Authors:  Heli Savolainen; Peter Meerlo; Philip H Elsinga; Albert D Windhorst; Rudi A J O Dierckx; Nicola A Colabufo; Aren van Waarde; Gert Luurtsema
Journal:  AAPS J       Date:  2016-09-06       Impact factor: 4.009

3.  Evidence against a role of P-glycoprotein in the clearance of the Alzheimer's disease Aβ1-42 peptides.

Authors:  Ivan Bello; Milena Salerno
Journal:  Cell Stress Chaperones       Date:  2015-01-16       Impact factor: 3.667

Review 4.  PET and SPECT radiotracers to assess function and expression of ABC transporters in vivo.

Authors:  Severin Mairinger; Thomas Erker; Markus Muller; Oliver Langer
Journal:  Curr Drug Metab       Date:  2011-10       Impact factor: 3.731

5.  1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells.

Authors:  Matthew R Durk; Gary N Y Chan; Christopher R Campos; John C Peart; Edwin C Y Chow; Eason Lee; Ronald E Cannon; Reina Bendayan; David S Miller; K Sandy Pang
Journal:  J Neurochem       Date:  2012-11-01       Impact factor: 5.372

Review 6.  Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood-brain barrier.

Authors:  Stephen B Hladky; Margery A Barrand
Journal:  Fluids Barriers CNS       Date:  2018-10-19

Review 7.  P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer's Disease.

Authors:  Giulia Sita; Patrizia Hrelia; Andrea Tarozzi; Fabiana Morroni
Journal:  Oxid Med Cell Longev       Date:  2017-11-26       Impact factor: 6.543
  7 in total

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