HYPOTHESIS: Pheochromocytoma can be safely treated laparoscopically; "subclinical" pheochromocytoma is increasingly common. DESIGN: Retrospective review. SETTING: University hospital. PATIENTS: Patients undergoing adrenalectomy for pheochromocytoma at our institution in 1994 to 2009. INTERVENTIONS: Laparoscopic, hand-assisted, and open adrenalectomy. MAIN OUTCOME MEASURES: Preoperative and postoperative clinical and biochemical data. RESULTS: One hundred two patients (52 women, 50 men) with pheochromocytoma underwent 108 operations. Ninety-seven operations were laparoscopic; 7, open; and 4, converted from laparoscopic to hand assisted or open. Six operations were bilateral; 3 were subtotal cortex-sparing resections. Thirty-four patients (33%) presented with adrenal incidentaloma and minimal symptoms, 28 within the past decade. Ten patients had paragangliomas, 7 of whom underwent laparoscopic resection. The mean (SD) tumor size was 5.3 (2.8) cm. Seven patients had recurrence requiring reoperation; the mean length of time between initial operation and recurrence was 6 years (range, 6 months to 17 years). There were no perioperative deaths. CONCLUSIONS: Laparoscopic adrenalectomy can be safely performed for pheochromocytoma in more than 90% of cases. More than one-third of patients presented with subclinical pheochromocytoma. Patients should be followed up closely because recurrence may develop several years after adrenalectomy.
HYPOTHESIS: Pheochromocytoma can be safely treated laparoscopically; "subclinical" pheochromocytoma is increasingly common. DESIGN: Retrospective review. SETTING: University hospital. PATIENTS: Patients undergoing adrenalectomy for pheochromocytoma at our institution in 1994 to 2009. INTERVENTIONS: Laparoscopic, hand-assisted, and open adrenalectomy. MAIN OUTCOME MEASURES: Preoperative and postoperative clinical and biochemical data. RESULTS: One hundred two patients (52 women, 50 men) with pheochromocytoma underwent 108 operations. Ninety-seven operations were laparoscopic; 7, open; and 4, converted from laparoscopic to hand assisted or open. Six operations were bilateral; 3 were subtotal cortex-sparing resections. Thirty-four patients (33%) presented with adrenal incidentaloma and minimal symptoms, 28 within the past decade. Ten patients had paragangliomas, 7 of whom underwent laparoscopic resection. The mean (SD) tumor size was 5.3 (2.8) cm. Seven patients had recurrence requiring reoperation; the mean length of time between initial operation and recurrence was 6 years (range, 6 months to 17 years). There were no perioperative deaths. CONCLUSIONS: Laparoscopic adrenalectomy can be safely performed for pheochromocytoma in more than 90% of cases. More than one-third of patients presented with subclinical pheochromocytoma. Patients should be followed up closely because recurrence may develop several years after adrenalectomy.
Authors: Laurent Brunaud; Phi-Linh Nguyen-Thi; Eric Mirallie; Marco Raffaelli; Menno Vriens; Pierre-Etienne Theveniaud; Myriam Boutami; Brendan M Finnerty; Wessel M C M Vorselaars; Inne Borel Rinkes; Rocco Bellantone; Celestino Lombardi; Thomas Fahey; Rasa Zarnegar; Laurent Bresler Journal: Surg Endosc Date: 2015-06-20 Impact factor: 4.584
Authors: M Thomaschewski; H Neeff; T Keck; H P H Neumann; T Strate; E von Dobschuetz Journal: Rev Endocr Metab Disord Date: 2017-12 Impact factor: 6.514
Authors: Trudie A Goers; Michael Abdo; Jeffrey F Moley; Brent D Matthews; Mary Quasebarth; L Michael Brunt Journal: Surg Endosc Date: 2012-08-31 Impact factor: 4.584