Literature DB >> 20855241

[Phyllodes tumors and breast sarcomas: a review].

J Grenier1, C Delbaldo, L Zelek, P Piedbois.   

Abstract

Phyllodes tumors and sarcomas of the breast are non-epithelial tumors of the breast. Phyllodes tumors are benign tumors, tumors of intermediate malignancy or malignant tumors. The differential diagnosis with a very proliferant fibroadenoma may be difficult. Histological sub-type, type of surgery (definitive or not) and stromal proliferation determine the prognosis. There is a risk of local relapse and distant metastases, in particular to the lung. Surgery (often radical) is the standard treatment. Radiotherapy is recommended in case of high-grade tumor and after conservativetreatment. Breast sarcomas are even rarer. All histological types exist with a predominance of histiofibrocytome type tumors. Grade, involved margins and sometimes tumor necrosis are major prognostics factors. Among the various sub-types, angiosarcoma is characterized by a high risk of occurrence in irradiated fields and by a poor prognosis with a high risk of lung metastases. The treatment is mostly based on mastectomy without lymph node dissection given the exceptional flooding axillary. In some situations, a conservative treatment can be discussed, based on tumor size, grade and volume of the breast. Locoregional radiotherapy is often proposed for tumors over 5 cm and/or of high grade. Systemic chemotherapy is not a standard but should be discussed in the forms at high risk of relapse (like angiosarcoma).

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Year:  2010        PMID: 20855241     DOI: 10.1684/bdc.2010.1174

Source DB:  PubMed          Journal:  Bull Cancer        ISSN: 0007-4551            Impact factor:   1.276


  3 in total

1.  Recurrent borderline phyllodes tumor in nipple: a rare case report and review of the literature.

Authors:  Denghua Sun; Lu Tang; Hua Xing; Lijuan Zhang; Le Zhang
Journal:  Gland Surg       Date:  2020-04

2.  "Ruptured" malignant phyllodes tumor of the breast: a case report.

Authors:  Chagkrit Ditsatham; Areewan Somwangprasert; Kirati Watcharachan; Phanchaporn Wongmaneerung
Journal:  Int Med Case Rep J       Date:  2016-02-22

3.  An 11 kg Phyllodes tumor of the breast in combination with other multiple chronic diseases: Case report and review of the literature.

Authors:  Zhilong Zhao; Jia Zhang; Yuanyuan Chen; Lanwan Shen; Jiansheng Wang
Journal:  Oncol Lett       Date:  2013-05-22       Impact factor: 2.967

  3 in total

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