Literature DB >> 20853498

Dendritic cells in cancer immunotherapy.

Gerold Schuler1.   

Abstract

DC initiate and regulate T-cell immunity and are thus the key to optimization of all types of vaccines. Insights into DC biology offer many opportunities to enhance immunogenicity. In this Viewpoint, I discuss some recent developments and findings that are of immediate relevance for the clinical development of cancer vaccines. In addition, I emphasize my personal view that we should explore the potential of adoptively transferred DC (i.e. DC vaccination) as cancer vaccines by performing two-armed trials that address critical variables and by delivering antigens via mRNA-transfected DC.

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Year:  2010        PMID： 20853498     DOI： 10.1002/eji.201040630

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  43 in total

Review 1.  Multifunctional nanoparticles for cancer immunotherapy.

Authors:  Tayebeh Saleh; Seyed Abbas Shojaosadati
Journal:  Hum Vaccin Immunother       Date:  2016-02-22       Impact factor: 3.452

2.  Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.

Authors:  David C Binder; Boris Engels; Ainhoa Arina; Ping Yu; James M Slauch; Yang-Xin Fu; Theodore Karrison; Byron Burnette; Christian Idel; Ming Zhao; Robert M Hoffman; David H Munn; Donald A Rowley; Hans Schreiber
Journal:  Cancer Immunol Res       Date:  2013-08       Impact factor: 11.151

3.  Targeting the immunoregulator SRA/CD204 potentiates specific dendritic cell vaccine-induced T-cell response and antitumor immunity.

Authors:  Huanfa Yi; Chunqing Guo; Xiaofei Yu; Ping Gao; Jie Qian; Daming Zuo; Masoud H Manjili; Paul B Fisher; John R Subjeck; Xiang-Yang Wang
Journal:  Cancer Res       Date:  2011-09-13       Impact factor: 12.701

Review 4.  ANTI-TUMOR IMMUNE RESPONSES INDUCED BY RADIOTHERAPY: A REVIEW.

Authors:  Yuya Yoshimoto; Koji Kono; Yoshiyuki Suzuki
Journal:  Fukushima J Med Sci       Date:  2015-07-02

Review 5.  Cancer immunotherapy comes of age.

Authors:  Ira Mellman; George Coukos; Glenn Dranoff
Journal:  Nature       Date:  2011-12-21       Impact factor: 49.962

6.  IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity.

Authors:  Beatriz M Carreno; Michelle Becker-Hapak; Alexander Huang; Megan Chan; Amer Alyasiry; Wen-Rong Lie; Rebecca L Aft; Lynn A Cornelius; Kathryn M Trinkaus; Gerald P Linette
Journal:  J Clin Invest       Date:  2013-07-11       Impact factor: 14.808

Review 7.  Dendritic-cell-based therapeutic cancer vaccines.

Authors:  Karolina Palucka; Jacques Banchereau
Journal:  Immunity       Date:  2013-07-25       Impact factor: 31.745

8.  Apoptosis - an Ubiquitous T cell Immunomodulator.

Authors:  Anuradha K Murali; Shikhar Mehrotra
Journal:  J Clin Cell Immunol       Date:  2011-12-10

Review 9.  Human dendritic cell subsets in vaccination.

Authors:  Karolina Palucka; Jacques Banchereau
Journal:  Curr Opin Immunol       Date:  2013-05-30       Impact factor: 7.486

10.  CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates.

Authors:  Gabrielle Romain; Ellen van Gulck; Olivier Epaulard; Sangkon Oh; Dapeng Li; Gerard Zurawski; Sandra Zurawski; Antonio Cosma; Lucille Adam; Catherine Chapon; Biliana Todorova; Jacques Banchereau; Nathalie Dereuddre-Bosquet; Guido Vanham; Roger Le Grand; Frédéric Martinon
Journal:  Eur J Immunol       Date:  2012-07-04       Impact factor: 5.532
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