Literature DB >> 20853492

Accumulation of plasmacytoid DC: Roles in disease pathogenesis and targets for immunotherapy.

Melissa Swiecki1, Marco Colonna.   

Abstract

Plasmacytoid DC (pDC) secrete type I IFN in response to viruses and RNA/DNA/immunocomplexes. Type I IFN confer resistance to viral infections and promote innate and adaptive immune responses. pDC also produce cytokines and chemokines that influence recruitment and function of T cells and differentiation of B cells. Thus, pDC have been implicated both in protective immune responses and in induction of tolerance. In this Viewpoint, we discuss how the recruitment and accumulation of pDC may impact pathogenesis of several diseases and how pDC can be targeted for therapeutic interventions.

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Year:  2010        PMID： 20853492      PMCID： PMC3732170          DOI： 10.1002/eji.201040602

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  123 in total

Review 1.  Innate immunity and HIV.

Authors:  F P Siegal; G T Spear
Journal:  AIDS       Date:  2001       Impact factor: 4.177

2.  Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals.

Authors:  Jihed Chehimi; Donald E Campbell; Livio Azzoni; Darlene Bacheller; Emmanouil Papasavvas; Ghassen Jerandi; Karam Mounzer; Jay Kostman; Giorgio Trinchieri; Luis J Montaner
Journal:  J Immunol       Date:  2002-05-01       Impact factor: 5.422

3.  Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology.

Authors:  C Asselin-Paturel; A Boonstra; M Dalod; I Durand; N Yessaad; C Dezutter-Dambuyant; A Vicari; A O'Garra; C Biron; F Brière; G Trinchieri
Journal:  Nat Immunol       Date:  2001-12       Impact factor: 25.606

4.  Decreased interferon-alpha production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors.

Authors:  S Feldman; D Stein; S Amrute; T Denny; Z Garcia; P Kloser; Y Sun; N Megjugorac; P Fitzgerald-Bocarsly
Journal:  Clin Immunol       Date:  2001-11       Impact factor: 3.969

5.  Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells.

Authors:  W Zou; V Machelon; A Coulomb-L'Hermin; J Borvak; F Nome; T Isaeva; S Wei; R Krzysiek; I Durand-Gasselin; A Gordon; T Pustilnik; D T Curiel; P Galanaud; F Capron; D Emilie; T J Curiel
Journal:  Nat Med       Date:  2001-12       Impact factor: 53.440

6.  Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection.

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Journal:  Blood       Date:  2001-11-15       Impact factor: 22.113

7.  Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients.

Authors:  V Soumelis; I Scott; F Gheyas; D Bouhour; G Cozon; L Cotte; L Huang; J A Levy; Y J Liu
Journal:  Blood       Date:  2001-08-15       Impact factor: 22.113

8.  Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load.

Authors:  H Donaghy; A Pozniak; B Gazzard; N Qazi; J Gilmour; F Gotch; S Patterson
Journal:  Blood       Date:  2001-10-15       Impact factor: 22.113

9.  IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation.

Authors:  Anne Krug; Ravindra Uppaluri; Fabio Facchetti; Brigitte G Dorner; Kathleen C F Sheehan; Robert D Schreiber; Marina Cella; Marco Colonna
Journal:  J Immunol       Date:  2002-12-01       Impact factor: 5.422

10.  BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction.

Authors:  A Dzionek; Y Sohma; J Nagafune; M Cella; M Colonna; F Facchetti; G Günther; I Johnston; A Lanzavecchia; T Nagasaka; T Okada; W Vermi; G Winkels; T Yamamoto; M Zysk; Y Yamaguchi; J Schmitz
Journal:  J Exp Med       Date:  2001-12-17       Impact factor: 14.307
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  15 in total

1.  The role of pDC, recipient T(reg) and donor T(reg) in HSC engraftment: Mechanisms of facilitation.

Authors:  Paul A Cardenas; Yiming Huang; Suzanne T Ildstad
Journal:  Chimerism       Date:  2011-07-01

Review 2.  Dysfunction of antigen processing and presentation by dendritic cells in cancer.

Authors:  Joanna Bandola-Simon; Paul A Roche
Journal:  Mol Immunol       Date:  2018-04-05       Impact factor: 4.407

Review 3.  Dendritic cells in cancer: the role revisited.

Authors:  Filippo Veglia; Dmitry I Gabrilovich
Journal:  Curr Opin Immunol       Date:  2017-02-10       Impact factor: 7.486

Review 4.  TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.

Authors:  Elena Gallo MacFarlane; Julia Haupt; Harry C Dietz; Eileen M Shore
Journal:  Cold Spring Harb Perspect Biol       Date:  2017-11-01       Impact factor: 10.005

Review 5.  The function of dendritic cells in modulating the host response.

Authors:  L Song; G Dong; L Guo; D T Graves
Journal:  Mol Oral Microbiol       Date:  2017-10-09       Impact factor: 3.563

6.  Wild-type coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo.

Authors:  Christopher C Kemball; Claudia T Flynn; Martin P Hosking; Jason Botten; J Lindsay Whitton
Journal:  Virology       Date:  2012-05-01       Impact factor: 3.616

7.  PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells.

Authors:  Eiji Esashi; Musheng Bao; Yi-Hong Wang; Wei Cao; Yong-Jun Liu
Journal:  Eur J Immunol       Date:  2012-03       Impact factor: 5.532

Review 8.  Tolerogenic plasmacytoid DC.

Authors:  Benjamin M Matta; Antonino Castellaneta; Angus W Thomson
Journal:  Eur J Immunol       Date:  2010-10       Impact factor: 5.532

9.  Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses.

Authors:  Gagan Bajwa; Ralph J DeBerardinis; Baomei Shao; Brian Hall; J David Farrar; Michelle A Gill
Journal:  J Immunol       Date:  2016-01-29       Impact factor: 5.422

10.  Plasmacytoid dendritic cells are inefficient in activation of human regulatory T cells.

Authors:  Mario Hubo; Helmut Jonuleit
Journal:  PLoS One       Date:  2012-08-29       Impact factor: 3.240
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