Literature DB >> 2085345

Genotyping study of alcohol dehydrogenase class I polymorphism in French patients with alcoholic cirrhosis. The French Group for Research on Alcohol and Liver.

P Couzigou1, B Fleury, A Groppi, A Cassaigne, J Begueret, A Iron.   

Abstract

Comparison of alcohol dehydrogenase polymorphism at the loci ADH2 and ADH3 is made in France between 46 alcoholic cirrhotic patients and 39 controls, by genotyping technique using polymerase chain reaction on blood microsample collected on blotting paper. The genotype distributions are similar, with low frequency of the ADH2(2) allele. Polymorphism at the ADH3 locus is not a genetic factor for alcoholic cirrhosis in France.

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Year:  1990        PMID： 2085345     DOI： 10.1093/oxfordjournals.alcalc.a045058

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN： 0735-0414            Impact factor:   2.826


  9 in total

1.  Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism.

Authors:  C C Chen; R B Lu; Y C Chen; M F Wang; Y C Chang; T K Li; S J Yin
Journal:  Am J Hum Genet       Date:  1999-09       Impact factor: 11.025

2.  Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism.

Authors:  M Osier; A J Pakstis; J R Kidd; J F Lee; S J Yin; H C Ko; H J Edenberg; R B Lu; K K Kidd
Journal:  Am J Hum Genet       Date:  1999-04       Impact factor: 11.025

3.  Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases.

Authors:  Dawei Li; Hongyu Zhao; Joel Gelernter
Journal:  Biol Psychiatry       Date:  2011-04-17       Impact factor: 13.382

4.  Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases.

Authors:  Dawei Li; Hongyu Zhao; Joel Gelernter
Journal:  Hum Genet       Date:  2012-04-05       Impact factor: 4.132

5.  Alcohol dehydrogenase 1C (ADH1C) gene polymorphism and alcoholic liver cirrhosis risk: a meta analysis.

Authors:  Lei He; Tao Deng; He-Sheng Luo
Journal:  Int J Clin Exp Med       Date:  2015-07-15

6.  Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.

Authors:  J P Visapää; K Götte; M Benesova; J Li; N Homann; C Conradt; H Inoue; M Tisch; K Hörrmann; S Väkeväinen; M Salaspuro; H K Seitz
Journal:  Gut       Date:  2004-06       Impact factor: 23.059

7.  Genetic polymorphism in alcohol dehydrogenase 2 (ADH2) gene and alcoholic liver cirrhosis risk.

Authors:  Lei He; Tao Deng; He-Sheng Luo
Journal:  Int J Clin Exp Med       Date:  2015-05-15

8.  Glutathione S-transferase class mu in French alcoholic cirrhotic patients.

Authors:  A Groppi; C Coutelle; B Fleury; A Iron; J Begueret; P Couzigou
Journal:  Hum Genet       Date:  1991-09       Impact factor: 4.132

9.  Association of restriction fragment length polymorphism in alcohol dehydrogenase 2 gene with alcohol induced liver damage.

Authors:  D I Sherman; R J Ward; M Warren-Perry; R Williams; T J Peters
Journal:  BMJ       Date:  1993-11-27
  9 in total

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