BACKGROUND AND PURPOSE: The present study retrospectively analyzed the clinical impact of endoscopic papillectomy on the selection of a treatment strategy for patients with benign-malignant borderline lesions of the major duodenal papilla. PATIENTS AND METHODS: Between November 1995 and July 2009, 28 patients were selected for endoscopic papillectomy. The clinical impact of endoscopic papillectomy was assessed. Snare resection was performed in a radical fashion. RESULTS: An endoscopic papillectomy was technically feasible in all patients. En bloc excision was achieved in 22 cases (79%). The final histopathological diagnoses of the endoscopic specimen were 17 adenoma (61%), 7 carcinoma in adenoma (25%), and 4 adenocarcinoma (14%). Two out of the four adenocarcinoma cases were referred for surgery. The other two patients with negative margins have not experienced recurrences during the follow-up period. A residual tumor was detected in 1 out of 17 cases (6%) of adenoma and 2 out of 7 cases (29%) of carcinoma in adenoma. CONCLUSIONS: Endoscopic papillectomy is therefore considered to be an effective treatment for patients with a benign-malignant borderline lesion of the major duodenal papilla. This method also has an important clinical impact because it provides an accurate diagnosis, aids in the selection of an appropriate treatment strategy, and reduces unnecessary surgery.
BACKGROUND AND PURPOSE: The present study retrospectively analyzed the clinical impact of endoscopic papillectomy on the selection of a treatment strategy for patients with benign-malignant borderline lesions of the major duodenal papilla. PATIENTS AND METHODS: Between November 1995 and July 2009, 28 patients were selected for endoscopic papillectomy. The clinical impact of endoscopic papillectomy was assessed. Snare resection was performed in a radical fashion. RESULTS: An endoscopic papillectomy was technically feasible in all patients. En bloc excision was achieved in 22 cases (79%). The final histopathological diagnoses of the endoscopic specimen were 17 adenoma (61%), 7 carcinoma in adenoma (25%), and 4 adenocarcinoma (14%). Two out of the four adenocarcinoma cases were referred for surgery. The other two patients with negative margins have not experienced recurrences during the follow-up period. A residual tumor was detected in 1 out of 17 cases (6%) of adenoma and 2 out of 7 cases (29%) of carcinoma in adenoma. CONCLUSIONS: Endoscopic papillectomy is therefore considered to be an effective treatment for patients with a benign-malignant borderline lesion of the major duodenal papilla. This method also has an important clinical impact because it provides an accurate diagnosis, aids in the selection of an appropriate treatment strategy, and reduces unnecessary surgery.
Authors: Bertrand Napoléon; M Victoria Alvarez-Sanchez; Philippe Leclercq; François Mion; Jean Pialat; Rodica Gincul; Daniel Ribeiro; Marie Cambou; Christine Lefort; Mar Rodríguez-Girondo; Jean Yves Scoazec Journal: Surg Endosc Date: 2013-04-03 Impact factor: 4.584
Authors: Kwang Hyun Chung; Sang Hyub Lee; Jin Ho Choi; Jinwoo Kang; Woo Hyun Paik; Dong-Won Ahn; Ji Kon Ryu; Yong-Tae Kim Journal: United European Gastroenterol J Date: 2017-11-28 Impact factor: 4.623
Authors: Marcus Hollenbach; Einas Abou Ali; Francesco Auriemma; Aiste Gulla; Christian Heise; Sara Regnér; Sébastien Gaujoux Journal: Front Med (Lausanne) Date: 2020-05-06
Authors: Woo Ik Chang; Yang Won Min; Hwan Sic Yun; Kwang Hyuck Lee; Jong Kyun Lee; Kyu Taek Lee; Poong Lyul Rhee Journal: Gut Liver Date: 2014-05 Impact factor: 4.519