| Literature DB >> 20850723 |
Won Heum Nah1, Jae Eun Lee, Hyun Jun Park, Nam Cheol Park, Myung Chan Gye.
Abstract
Expression of claudin-11, which builds up blood-testis barrier (BTB), was increased in decreased spermatogenesis, including in hypospermatogenesis, spermatocytic and maturation arrest, and Sertoli cell only (SCO) testes. Increased claudin-11 immunoreactivity was observed at the inter-Sertoli tight junctions in maturation arrest and in the cytoplasm of Sertoli cells in SCO. The late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the BTB in the human testis.Entities:
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Year: 2010 PMID： 20850723 DOI： 10.1016/j.fertnstert.2010.08.023
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329