Literature DB >> 2084949

Multimeric analysis of von Willebrand factor by molecular sieving electrophoresis in sodium dodecyl sulphate agarose gel.

G Raines1, H Aumann, S Sykes, A Street.   

Abstract

We report the development and optimisation of an agarose gel electrophoretic method for the separation and detection of von Willebrand Factor (vWF) multimers. The method has been specifically developed for use in the clinical evaluation and classification of patients with von Willebrand's Disease (vWD) and clearly shows structural multimer abnormalities associated with the bleeding diathesis of this inherited bleeding disorder.

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Year:  1990        PMID： 2084949     DOI： 10.1016/0049-3848(90)90181-b

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  13 in total

1.  Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets.

Authors:  K A Cooney; S E Lyons; D Ginsburg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

2.  Differential modulation of adhesion molecule expression by hydroxycarbamide in human endothelial cells from the micro- and macrocirculation: potential implications in sickle cell disease vasoocclusive events.

Authors:  Sandrine Laurance; Pauline Lansiaux; François-Xavier Pellay; Michelle Hauchecorne; Arndt Benecke; Jacques Elion; Claudine Lapoumeroulie
Journal:  Haematologica       Date:  2011-01-12       Impact factor: 9.941

3.  Phylogenetic and functional analysis of histidine residues essential for pH-dependent multimerization of von Willebrand factor.

Authors:  Luke T Dang; Angie R Purvis; Ren-Huai Huang; Lisa A Westfield; J Evan Sadler
Journal:  J Biol Chem       Date:  2011-05-17       Impact factor: 5.157

4.  Triplet structure of human von Willebrand factor.

Authors:  B E Fischer; K B Thomas; U Schlokat; F Dorner
Journal:  Biochem J       Date:  1998-04-15       Impact factor: 3.857

5.  Accelerated clearance alone explains ultra-large multimers in von Willebrand disease Vicenza.

Authors:  A Gézsi; U Budde; I Deák; E Nagy; A Mohl; A Schlammadinger; Z Boda; T Masszi; J E Sadler; I Bodó
Journal:  J Thromb Haemost       Date:  2010-01-17       Impact factor: 5.824

6.  Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi.

Authors:  Angie R Purvis; Julia Gross; Luke T Dang; Ren-Huai Huang; Milan Kapadia; R Reid Townsend; J Evan Sadler
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-25       Impact factor: 11.205

7.  von Willebrand disease type B: a missense mutation selectively abolishes ristocetin-induced von Willebrand factor binding to platelet glycoprotein Ib.

Authors:  I Rabinowitz; E A Tuley; D J Mancuso; A M Randi; B G Firkin; M A Howard; J E Sadler
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

8.  The influence of vasovagal response on the coagulation system.

Authors:  Markus Kraemer; Markus Kuepper; Andrea Nebe-vom Stein; Ulrich Sorgenfrei; Rolf R Diehl
Journal:  Clin Auton Res       Date:  2009-07-25       Impact factor: 4.435

9.  Expression of von Willebrand factor "Normandy": an autosomal mutation that mimics hemophilia A.

Authors:  E A Tuley; C Gaucher; S Jorieux; N K Worrall; J E Sadler; C Mazurier
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

10.  Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress.

Authors:  Kyuhwan Shim; Patricia J Anderson; Elodee A Tuley; Erin Wiswall; J Evan Sadler
Journal:  Blood       Date:  2007-09-27       Impact factor: 22.113
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