Literature DB >> 20848559

Prescribing of inappropriate medication in nursing home residents in Germany according to a French consensus list: a cross-sectional cohort study.

Marita Kölzsch1, Kirsten Kopke, Thomas Fischer, Werner Hofmann, Ronny Kuhnert, Juliane Bolbrinker, Adelheid Kuhlmey, Dagmar Dräger, Reinhold Kreutz.   

Abstract

PURPOSE: The current use of inappropriate medication in elderly nursing home residents (NHRs) in Germany is unclear. We therefore set out to analyse the frequency and patterns of potentially inappropriate drug prescriptions in elderly NHRs in Germany.
METHODS: We utilised prescription data for NHRs 65 years or older from a large German health insurance company during a period of 3 months. Inappropriate drugs were identified from a recently reported French consensus list.
RESULTS: Data for 7271 (83.7%) females and 1414 (16.3%) males were available for analysis. The average age was 83.6 ± 7.3 years. Overall 48 inappropriate drugs were prescribed resulting in a total of 3825 inappropriate drug prescriptions which accounted for 4.3% of all documented prescriptions (n = 88,695). One thousand nine hundred and three (21.9%) residents received at least one inappropriate drug prescription. Using logistic regression we detected no significant influence of gender or level of care on frequency of inappropriate prescriptions. However, age had a significant influence; with increasing age the frequency of residents receiving inappropriate medications decreased steadily (r = -0.92, p = 0.003) and ranged from a maximum of 32.8% in the group between 65 and 69 years to a minimum of 15.2% in residents older than 94 years. This observation was paralleled by a significant and continuous decrease of drug prescription rates with increasing age (r = -0.88, p = 0.009).
CONCLUSION: The present analysis demonstrates that about one out of five elderly NHRs received at least one inappropriate drug prescription. Additional studies may aim to establish a list of frequently prescribed inappropriate drugs for Germany.
Copyright © 2010 John Wiley & Sons, Ltd.

Mesh:

Year:  2011        PMID: 20848559     DOI: 10.1002/pds.2005

Source DB:  PubMed          Journal:  Pharmacoepidemiol Drug Saf        ISSN: 1053-8569            Impact factor:   2.890


  10 in total

Review 1.  [Potentially inappropriate medication: the quality of pharmacotherapy in the elderly].

Authors:  U Thiem
Journal:  Internist (Berl)       Date:  2012-09       Impact factor: 0.743

2.  [Autonomy despite multimorbidity in old age--the Berlin-based AMA research consortium].

Authors:  B Schüz; D Dräger; S Richter; K Kummer; A Kuhlmey; C Tesch-Römer
Journal:  Z Gerontol Geriatr       Date:  2011-12       Impact factor: 1.281

3.  Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria.

Authors:  Chirn-Bin Chang; Jen-Hau Chen; Chiung-Jung Wen; Hsu-Ko Kuo; I-Shu Lu; Lee-Shu Chiu; Shwu-Chong Wu; Ding-Cheng Derrick Chan
Journal:  Br J Clin Pharmacol       Date:  2011-09       Impact factor: 4.335

4.  Prescribing of potentially inappropriate medications for the elderly: an analysis based on the PRISCUS list.

Authors:  Ute Amann; Niklas Schmedt; Edeltraut Garbe
Journal:  Dtsch Arztebl Int       Date:  2012-02-03       Impact factor: 5.594

5.  Prevalence and associations of potentially inappropriate prescriptions in Austrian nursing home residents: secondary analysis of a cross-sectional study.

Authors:  Eva Mann; Burkhard Haastert; Birgit Böhmdorfer; Thomas Frühwald; Bernhard Iglseder; Regina Roller-Wirnsberger; Gabriele Meyer
Journal:  Wien Klin Wochenschr       Date:  2013-03-28       Impact factor: 1.704

6.  Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list.

Authors:  Eva Mann; Birgit Böhmdorfer; Thomas Frühwald; Regina E Roller-Wirnsberger; Peter Dovjak; Christine Dückelmann-Hofer; Peter Fischer; Susanne Rabady; Bernhard Iglseder
Journal:  Wien Klin Wochenschr       Date:  2011-12-02       Impact factor: 1.704

7.  Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates.

Authors:  Lucas Morin; Johan Fastbom; Marie-Laure Laroche; Kristina Johnell
Journal:  Br J Clin Pharmacol       Date:  2015-05-26       Impact factor: 4.335

8.  Potentially inappropriate psychotropic prescription at discharge is associated with lower functioning in the elderly psychiatric inpatients. A cross-sectional study.

Authors:  Guillaume Fond; Claire Fajula; Daniel Dassa; Lore Brunel; Christophe Lançon; Laurent Boyer
Journal:  Psychopharmacology (Berl)       Date:  2016-04-30       Impact factor: 4.530

9.  Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP(3)S-tool.

Authors:  Eline Tommelein; Els Mehuys; Mirko Petrovic; Annemie Somers; Charlotte Van Damme; Eva Pattyn; Kristof Mattelin; Koen Boussery
Journal:  Int J Clin Pharm       Date:  2016-08-08

10.  Patient- and clinic visit-related factors associated with potentially inappropriate medication use among older home healthcare service recipients.

Authors:  Chirn-Bin Chang; Hsiu-Yun Lai; Shu-Yu Yang; Ru-Shu Wu; Hsing-Cheng Liu; Hsiu-Ying Hsu; Shinn-Jang Hwang; Ding-Cheng Chan
Journal:  PLoS One       Date:  2014-04-10       Impact factor: 3.240

  10 in total

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