Literature DB >> 20848467

Role of transforming growth factor-β in inflammatory bowel disease and colitis-associated colon cancer.

Linda A Feagins1.   

Abstract

Transforming growth factor-β (TGF-β) plays a central role in a wide array of cellular functions including control of cell growth and differentiation, embryonic development, wound healing, angiogenesis, and immune regulation. In the gastrointestinal tract, TGF-β can either promote or suppress inflammation and cancer formation. This report reviews recent data on the role of TGF-β in the pathogenesis of inflammatory bowel disease and how TGF-β might contribute to the cancer risk associated with chronic inflammation of the gut.

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Year:  2010        PMID： 20848467     DOI： 10.1002/ibd.21281

Source DB:  PubMed          Journal:  Inflamm Bowel Dis        ISSN： 1078-0998            Impact factor:   5.325


  44 in total

1.  Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation.

Authors:  Lindsay L Jones; Rajshekhar Alli; Bofeng Li; Terrence L Geiger
Journal:  J Immunol       Date:  2016-02-24       Impact factor: 5.422

Review 2.  British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.

Authors:  Christopher Andrew Lamb; Nicholas A Kennedy; Tim Raine; Philip Anthony Hendy; Philip J Smith; Jimmy K Limdi; Bu'Hussain Hayee; Miranda C E Lomer; Gareth C Parkes; Christian Selinger; Kevin J Barrett; R Justin Davies; Cathy Bennett; Stuart Gittens; Malcolm G Dunlop; Omar Faiz; Aileen Fraser; Vikki Garrick; Paul D Johnston; Miles Parkes; Jeremy Sanderson; Helen Terry; Daniel R Gaya; Tariq H Iqbal; Stuart A Taylor; Melissa Smith; Matthew Brookes; Richard Hansen; A Barney Hawthorne
Journal:  Gut       Date:  2019-09-27       Impact factor: 23.059

Review 3.  Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection.

Authors:  Shomyseh Sanjabi; Soyoung A Oh; Ming O Li
Journal:  Cold Spring Harb Perspect Biol       Date:  2017-06-01       Impact factor: 10.005

4.  Synergy of Transforming Growth Factor Beta 1 and All Trans Retinoic Acid in the Treatment of Inflammatory Bowel Disease: Role of Regulatory T cells.

Authors:  Dominick L Auci; Nejat K Egilmez
Journal:  J Gastroenterol Pancreatol Liver Disord       Date:  2016-08-11

Review 5.  Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases.

Authors:  Clara Abraham; Parambir S Dulai; Séverine Vermeire; William J Sandborn
Journal:  Gastroenterology       Date:  2016-10-22       Impact factor: 22.682

6.  Isolation and cytokine analysis of lamina propria lymphocytes from mucosal biopsies of the human colon.

Authors:  Rowann Bowcutt; Lisa B Malter; Lea Ann Chen; Martin J Wolff; Ian Robertson; Daniel B Rifkin; Michael Poles; Ilseug Cho; P'ng Loke
Journal:  J Immunol Methods       Date:  2015-03-10       Impact factor: 2.303

7.  Local level of TGF-β1 determines the effectiveness of dexamethasone through regulating the balance of Treg/Th17 cells in TNBS-induced mouse colitis.

Authors:  Peng You; Ning Chen; Lin Su; Tao Peng; Guodong Chen; Yulan Liu
Journal:  Exp Ther Med       Date:  2018-02-08       Impact factor: 2.447

8.  Increased duodenal expression of miR-146a and -155 in pediatric Crohn's disease.

Authors:  Dániel Szűcs; Nóra Judit Béres; Réka Rokonay; Kriszta Boros; Katalin Borka; Zoltán Kiss; András Arató; Attila J Szabó; Ádám Vannay; Erna Sziksz; Csaba Bereczki; Gábor Veres
Journal:  World J Gastroenterol       Date:  2016-07-14       Impact factor: 5.742

Review 9.  Heme oxygenase-1 as a target for TGF-β in kidney disease.

Authors:  Abolfazl Zarjou; Anupam Agarwal
Journal:  Semin Nephrol       Date:  2012-05       Impact factor: 5.299

10.  Peyer's patches-derived CD11b+ B cells recruit regulatory T cells through CXCL9 in dextran sulphate sodium-induced colitis.

Authors:  Zhiming Wang; Hushan Zhang; Ronghua Liu; Tingting Qian; Jiajing Liu; Enyu Huang; Zhou Lu; Chujun Zhao; Luman Wang; Yiwei Chu
Journal:  Immunology       Date:  2018-07-26       Impact factor: 7.397
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