Pen-Yuan Chu1, Tsung-Lun Lee, Shyue-Yih Chang. 1. Department of Otolaryngology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan, Republic of China. pychu@vghtpe.gov.tw
Abstract
BACKGROUND: We compared postoperative complications and oncologic results after laryngectomy of patients with laryngeal squamous cell carcinoma (SCC), with and without airway obstruction. METHODS: We retrospectively reviewed the medical records of 544 patients with laryngeal SCC between 1990 and 2000. Of 175 advanced cases receiving total laryngectomy, 32 initially presented with upper airway obstruction. RESULTS: Postoperative complications after laryngectomy did not differ significantly between patients with and without airway obstruction (36% vs 28%; p = .353). Although patients with airway obstruction had more T4 (81% vs 42%; p < .001) and stage IV disease (82% vs 48%; p = .0004), tumor recurrence rates did not increase (21% vs 29%; p = .374). Five-year overall (52% vs 60%; p = .251), disease-specific (73% vs 70%; p = .982), and relapse-free (72% vs 68%; p = .982) survival did not differ significantly between groups. CONCLUSION: After appropriate management of airway obstruction, the postoperative complications and oncologic results were similar to those without airway obstruction.
BACKGROUND: We compared postoperative complications and oncologic results after laryngectomy of patients with laryngeal squamous cell carcinoma (SCC), with and without airway obstruction. METHODS: We retrospectively reviewed the medical records of 544 patients with laryngeal SCC between 1990 and 2000. Of 175 advanced cases receiving total laryngectomy, 32 initially presented with upper airway obstruction. RESULTS:Postoperative complications after laryngectomy did not differ significantly between patients with and without airway obstruction (36% vs 28%; p = .353). Although patients with airway obstruction had more T4 (81% vs 42%; p < .001) and stage IV disease (82% vs 48%; p = .0004), tumor recurrence rates did not increase (21% vs 29%; p = .374). Five-year overall (52% vs 60%; p = .251), disease-specific (73% vs 70%; p = .982), and relapse-free (72% vs 68%; p = .982) survival did not differ significantly between groups. CONCLUSION: After appropriate management of airway obstruction, the postoperative complications and oncologic results were similar to those without airway obstruction.
Authors: Carlos Hernández-Brito; María Alejandra Salazar-Álvarez; Mario Enrique Álvarez-Bojórquez; Francisco Carlos Cisneros-Juvera; Javier López-Gómez; Ángel Elizalde-Méndez; Martín Granados-García Journal: Int J Surg Case Rep Date: 2018-08-09