| Literature DB >> 20848071 |
A Pierchalla1, K W Schulte, B Homey.
Abstract
Linear localized scleroderma is a variant of localized scleroderma characterized by linear bands and sclerotic plaques of the skin, which can result in contractures, muscle atrophy and debilitating deformities. The etiology remains unknown and no specific therapy is available. Regimens combining pulsed high-dose corticosteroids with methotrexate therapy seem promising. Our patient responded well to intravenous prednisolone (500 mg/d) for 3 consecutive days monthly combined with an oral dose of methotrexate of (15 mg/wk).Entities:
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Year: 2010 PMID: 20848071 DOI: 10.1007/s00105-010-2047-z
Source DB: PubMed Journal: Hautarzt ISSN: 0017-8470 Impact factor: 0.751