Literature DB >> 20847748

A 'living' prosthetic iris.

J Lapointe1, J-F Durette, A Harhira, A Shaat, P R Boulos, R Kashyap.   

Abstract

AIM: To design and demonstrate dynamic pupils, which react to light for use with ocular prostheses.
METHODS: The realism of ocular prostheses is limited by the immobility of the pupil. Our solution is to use a liquid crystal display (LCD) in the prosthesis to vary the pupil size as a function of the ambient light. Several liquid crystal cells were fabricated and tested for survivability through the ocular prosthesis manufacturing process. The dynamic pupil is controlled by a novel and entirely autonomous, self-powered passive electronic circuit using a solar cell, matching the minimum diameter of the pupil.
RESULTS: The first LCD surviving the rugged conditions of the ocular prosthesis manufacturing steps and an entirely passive circuit controlling the pupil have been demonstrated for the first time to our knowledge. A design for a complete prosthesis with a dynamic pupil has been proposed. Finally, a standard device for the mass production of ocular prostheses is presented.
CONCLUSION: We have shown that a practical solution for an autonomous self-powered dynamic pupil is possible, given the constraints of size, fabrication process, weight, cost and manufacturability on a mass scale. We envision that the LCD could be mass produced, and only the final steps for the integration of the iris matched to a patient would be necessary before assembly using standard processing steps for the production of the prosthesis. Using a clinical trial, we hope to demonstrate that the dynamic pupil will have a positive impact on the quality of life of patients.

Entities:  

Mesh:

Year:  2010        PMID: 20847748     DOI: 10.1038/eye.2010.128

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  5 in total

1.  Author's response: Prosthetic rehabilitation after orbital exenteration: a case series.

Authors:  Gunjan Pruthi; Veena Jain; Suresh Rajendiran; Ritu Jha
Journal:  Indian J Ophthalmol       Date:  2015-01       Impact factor: 1.848

2.  Surgical reconstruction or prosthetic rehabilitation following orbital exenteration: The clinician's dilemma.

Authors:  Himanshi Aggarwal; Pradeep Kumar
Journal:  Indian J Plast Surg       Date:  2014-01

3.  A simple technique to overcome self-focusing, filamentation, supercontinuum generation, aberrations, depth dependence and waveguide interface roughness using fs laser processing.

Authors:  Jerome Lapointe; Raman Kashyap
Journal:  Sci Rep       Date:  2017-03-29       Impact factor: 4.379

Review 4.  A review of techniques of iris replication and a novel method of fabrication of ocular prosthesis using two different iris location methods.

Authors:  Anshul Trivedi; Roma Goswami; Nivedita Bawa; Shama Waheed; Jitendra Rao
Journal:  Natl J Maxillofac Surg       Date:  2021-03-16

5.  Engineering a Light-Attenuating Artificial Iris.

Authors:  Farah J Shareef; Shan Sun; Mrignayani Kotecha; Iris Kassem; Dimitri Azar; Michael Cho
Journal:  Invest Ophthalmol Vis Sci       Date:  2016-04-01       Impact factor: 4.799

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.