Literature DB >> 20847744

Central roles of NLRs and inflammasomes in viral infection.

Thirumala-Devi Kanneganti1.   

Abstract

The immune response to viral infections is determined by a complex interplay between the pathogen and the host. Innate immune cells express a set of cytosolic sensors to detect viral infection. Recognition by these sensors induces the production of type I interferons and the assembly of inflammasome complexes that activate caspase-1, leading to production of interleukin-1β (IL-1β) and IL-18. Here, I discuss recent progress in our understanding of the central roles of NOD-like receptors (NLRs) and inflammasomes in the immune response during viral infections. This information will improve our understanding of host defence mechanisms against viruses and provide new avenues for interfering in the pathogenesis of infectious diseases.

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Year:  2010        PMID： 20847744      PMCID： PMC3909537          DOI： 10.1038/nri2851

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  100 in total

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2.  Respiratory syncytial virus infection of human alveolar epithelial cells enhances interferon regulatory factor 1 and interleukin-1beta-converting enzyme gene expression but does not cause apoptosis.

Authors:  R Takeuchi; H Tsutsumi; M Osaki; K Haseyama; N Mizue; S Chiba
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

3.  Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus.

Authors:  F Messud-Petit; J Gelfi; M Delverdier; M F Amardeilh; R Py; G Sutter; S Bertagnoli
Journal:  J Virol       Date:  1998-10       Impact factor: 5.103

4.  Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.

Authors:  N J Horwood; N Udagawa; J Elliott; D Grail; H Okamura; M Kurimoto; A R Dunn; T Martin; M T Gillespie
Journal:  J Clin Invest       Date:  1998-02-01       Impact factor: 14.808

5.  Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1 beta-converting enzyme.

Authors:  F Petit; S Bertagnoli; J Gelfi; F Fassy; C Boucraut-Baralon; A Milon
Journal:  J Virol       Date:  1996-09       Impact factor: 5.103

6.  Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

Authors:  T Ghayur; S Banerjee; M Hugunin; D Butler; L Herzog; A Carter; L Quintal; L Sekut; R Talanian; M Paskind; W Wong; R Kamen; D Tracey; H Allen
Journal:  Nature       Date:  1997-04-10       Impact factor: 49.962

7.  Cloning of a new cytokine that induces IFN-gamma production by T cells.

Authors:  H Okamura; H Tsutsi; T Komatsu; M Yutsudo; A Hakura; T Tanimoto; K Torigoe; T Okura; Y Nukada; K Hattori
Journal:  Nature       Date:  1995-11-02       Impact factor: 49.962

8.  Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.

Authors:  T Komiyama; C A Ray; D J Pickup; A D Howard; N A Thornberry; E P Peterson; G Salvesen
Journal:  J Biol Chem       Date:  1994-07-29       Impact factor: 5.157

9.  Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode M(r) 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model.

Authors:  S Kettle; N W Blake; K M Law; G L Smith
Journal:  Virology       Date:  1995-01-10       Impact factor: 3.616

Review 10.  Biologic basis for interleukin-1 in disease.

Authors:  C A Dinarello
Journal:  Blood       Date:  1996-03-15       Impact factor: 22.113
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  199 in total

Review 1.  Control of antiviral immunity by pattern recognition and the microbiome.

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Journal:  Immunol Rev       Date:  2012-01       Impact factor: 12.988

2.  Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling.

Authors:  Puck B van Kasteren; Corrine Beugeling; Dennis K Ninaber; Natalia Frias-Staheli; Sander van Boheemen; Adolfo García-Sastre; Eric J Snijder; Marjolein Kikkert
Journal:  J Virol       Date:  2011-11-09       Impact factor: 5.103

3.  Inflammasomes in cardiovascular diseases.

Authors:  Nisha Jain Garg
Journal:  Am J Cardiovasc Dis       Date:  2011-09-10

4.  NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens.

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Journal:  Cell Res       Date:  2012-04-10       Impact factor: 25.617

Review 5.  Oxidative stress and inflammation interactions in human obesity.

Authors:  Isabel Bondia-Pons; Lisa Ryan; J Alfredo Martinez
Journal:  J Physiol Biochem       Date:  2012-02-17       Impact factor: 4.158

6.  Inhibition of the inflammasome response by a viral protein that interacts with NLRs.

Authors:  Sean M Gregory; Blossom Damania
Journal:  Commun Integr Biol       Date:  2011-07-01

7.  Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by both NLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways.

Authors:  Masmudur M Rahman; Grant McFadden
Journal:  J Virol       Date:  2011-09-28       Impact factor: 5.103

Review 8.  AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity.

Authors:  Si Ming Man; Rajendra Karki; Thirumala-Devi Kanneganti
Journal:  Eur J Immunol       Date:  2015-12-28       Impact factor: 5.532

9.  Non-random lymphocyte distribution among virus-infected cells of the respiratory tract.

Authors:  Rajeev Rudraraju; Robert E Sealy; Sherri L Surman; Paul G Thomas; Barry H Dayton; Julia L Hurwitz
Journal:  Viral Immunol       Date:  2013-12       Impact factor: 2.257

Review 10.  Crosstalk between autophagy and inflammasomes.

Authors:  Jae-Min Yuk; Eun-Kyeong Jo
Journal:  Mol Cells       Date:  2013-11-06       Impact factor: 5.034
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