Literature DB >> 20847679

Ocular demodicosis as a potential cause of pediatric blepharoconjunctivitis.

Lingyi Liang1, Steve Safran, Yingying Gao, Hosam Sheha, V K Raju, Scheffer C G Tseng.   

Abstract

PURPOSE: To report Demodex infestation in pediatric blepharoconjunctivitis.
METHODS: A retrospective review of 12 patients, with ages from 2.5-11 years, with chronic blepharoconjunctivitis who failed to respond to conventional treatments. Demodex was detected by lash sampling and microscopic examination. Patients were treated with 50% tea tree oil (TTO) eyelid scrubs or 5% TTO ointment eyelid massages for 4-6 weeks.
RESULTS: Demodex mites were found in all, but 1 case had cylindrical dandruff in the lashes. After 1 week of TTO treatment, all patients showed dramatic resolution of ocular irritation and inflammation while Demodex counts dropped. All corneal signs resolved within 2 weeks except for a residual anterior stromal scar in 1 eye. During a follow-up period of 8.3 ± 4.6 months, 1 patient showed recurrent inflammation, which was successfully managed by a second round of TTO treatment.
CONCLUSIONS: Demodicosis should be considered as a potential cause of pediatric refractory blepharoconjunctivitis. Eyelid scrubs or massage with TTO could be an effective treatment regimen in these cases.

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Year:  2010        PMID: 20847679     DOI: 10.1097/ICO.0b013e3181e2eac5

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  18 in total

Review 1.  Pathogenic role of Demodex mites in blepharitis.

Authors:  Jingbo Liu; Hosam Sheha; Scheffer C G Tseng
Journal:  Curr Opin Allergy Clin Immunol       Date:  2010-10

Review 2.  Ocular Demodicosis as a Potential Cause of Ocular Surface Inflammation.

Authors:  Xiaohui Luo; Jing Li; Chuan Chen; Scheffer Tseng; Lingyi Liang
Journal:  Cornea       Date:  2017-11       Impact factor: 2.651

3.  Occurrence of Demodex species in patients with blepharitis and in healthy individuals: a 10-year observational study.

Authors:  Monika Maria Biernat; Jolanta Rusiecka-Ziółkowska; Elżbieta Piątkowska; Iwona Helemejko; Paweł Biernat; Grażyna Gościniak
Journal:  Jpn J Ophthalmol       Date:  2018-09-25       Impact factor: 2.447

4.  Demodex blepharokeratoconjunctivitis affecting young patients: A case series.

Authors:  Nikunj Vinodbhai Patel; Umang Mathur; Arpan Gandhi; Manisha Singh
Journal:  Indian J Ophthalmol       Date:  2020-05       Impact factor: 1.848

Review 5.  Demodex blepharitis: clinical perspectives.

Authors:  Stephanie R Fromstein; Jennifer S Harthan; Jaymeni Patel; Dominick L Opitz
Journal:  Clin Optom (Auckl)       Date:  2018-07-04

6.  Evaluation of the ocular surface characteristics and Demodex infestation in paediatric and adult blepharokeratoconjunctivitis.

Authors:  Mengliang Wu; Xiaochun Wang; Jing Han; Tingting Shao; Yan Wang
Journal:  BMC Ophthalmol       Date:  2019-03-07       Impact factor: 2.209

7.  Potential Role and Significance of Ocular Demodicosis in Patients with Concomitant Refractory Herpetic Keratitis.

Authors:  Kuo-Hsuan Hung; Yu-Hsiang Lan; Jui-Yen Lin; Eugene Yu-Chuan Kang; Hsin-Yuan Tan; Hung-Chi Chen; Ching-Hsi Hsiao; Lung-Kun Yeh
Journal:  Clin Ophthalmol       Date:  2020-12-23

8.  Terpinen-4-ol is the Most Active Ingredient of Tea Tree Oil to Kill Demodex Mites.

Authors:  Sean Tighe; Ying-Ying Gao; Scheffer C G Tseng
Journal:  Transl Vis Sci Technol       Date:  2013-11-13       Impact factor: 3.283

9.  Age differences in ocular demodicosis: Demodex profiles and clinical manifestations.

Authors:  Jing Li; Xiaohui Luo; Yinglin Liao; Lingyi Liang
Journal:  Ann Transl Med       Date:  2021-05

10.  Demodex spp. as a possible aetiopathogenic factor of acne and relation with acne severity and type.

Authors:  Ulviye Güvendi Akçınar; Emine Ünal; Funda Doğruman Al
Journal:  Postepy Dermatol Alergol       Date:  2018-04-24       Impact factor: 1.837

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