Deepa John1, Maya Thomas, Pushpa Jacob. 1. Department of Ophthalmology, Christian Medical College, Vellore, Tamil Nadu, India. deeparebeccajohn@gmail.com
Abstract
PURPOSE: To report a rare case of congenital insensitivity to pain with anhidrosis. METHODS: A 3-year-old girl presented with watering in the right eye for 3 days. Slit-lamp examination showed an epithelial defect and hypopyon in the right eye and a corneal scar with thinning and vascularization in the left eye. There was bilateral reduced corneal sensation and evidence of self-mutilated lips and fingers. RESULTS: Neurological manifestations along with ocular features confirmed the diagnosis of congenital insensitivity to pain with anhidrosis. CONCLUSIONS: Patients with congenital insensitivity to pain with anhidrosis are asymptomatic even when they develop corneal ulcer. Parents should be advised regular follow-up and prompt treatment because this is a vision-threatening corneal abnormality.
PURPOSE: To report a rare case of congenital insensitivity to pain with anhidrosis. METHODS: A 3-year-old girl presented with watering in the right eye for 3 days. Slit-lamp examination showed an epithelial defect and hypopyon in the right eye and a corneal scar with thinning and vascularization in the left eye. There was bilateral reduced corneal sensation and evidence of self-mutilated lips and fingers. RESULTS: Neurological manifestations along with ocular features confirmed the diagnosis of congenital insensitivity to pain with anhidrosis. CONCLUSIONS:Patients with congenital insensitivity to pain with anhidrosis are asymptomatic even when they develop corneal ulcer. Parents should be advised regular follow-up and prompt treatment because this is a vision-threatening corneal abnormality.
Authors: Alessandro Meduri; Giovanni William Oliverio; Antonio Valastro; Claudia Azzaro; Umberto Camellin; Francesco Franchina; Leandro Inferrera; Anna Roszkowska; Pasquale Aragona Journal: Front Med (Lausanne) Date: 2022-05-30