PURPOSE: To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy. METHODS: Case report. RESULTS: A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease. CONCLUSIONS: The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
PURPOSE: To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy. METHODS: Case report. RESULTS: A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease. CONCLUSIONS: The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
Authors: Franz Fogt; Thomas Rüediger; Albert J Augustin; Dale M Frank; Andreas Rosenwald; Axel Wellmann; Vivian Lee Journal: Ocul Oncol Pathol Date: 2019-04-10
Authors: Jose D Sandoval-Sus; Ana C Sandoval-Leon; Jennifer R Chapman; Jose Velazquez-Vega; Maria J Borja; Shai Rosenberg; Alexander Lossos; Izidore S Lossos Journal: Medicine (Baltimore) Date: 2014-05 Impact factor: 1.889
Authors: Rafael Trindade Tatit; Paulo Eduardo Albuquerque Zito Raffa; Giovana Cassia de Almeida Motta; André Alexandre Bocchi; Júlia Loripe Guimaraes; Paulo Roberto Franceschini; Paulo Henrique Pires de Aguiar Journal: Surg Neurol Int Date: 2021-06-21