BACKGROUND/AIMS: This study aimed to determine the clinical and neuroimaging correlates of the presence of neuropsychiatric symptoms in stroke patients with age-related confluent white matter hyperintensities (WMH). METHODS: The Neuropsychiatric Inventory was utilized to detect the presence of 12 symptoms. Multivariate logistic regression models were used to identify clinical and neuroimaging correlates of the presence of symptoms. RESULTS: Seventy-seven stroke patients (mean WMH volume: 39.5 cm(3)) were recruited. Thirty patients (39%) had ≥ 1 neuropsychiatric symptom. Poor executive function was associated with the presence of any symptoms and symptoms other than depression. More severe left frontal WMH was associated with depression. CONCLUSION: Executive dysfunction and left frontal WMH are correlated with neuropsychiatric symptoms in these patients.
BACKGROUND/AIMS: This study aimed to determine the clinical and neuroimaging correlates of the presence of neuropsychiatric symptoms in strokepatients with age-related confluent white matter hyperintensities (WMH). METHODS: The Neuropsychiatric Inventory was utilized to detect the presence of 12 symptoms. Multivariate logistic regression models were used to identify clinical and neuroimaging correlates of the presence of symptoms. RESULTS: Seventy-seven strokepatients (mean WMH volume: 39.5 cm(3)) were recruited. Thirty patients (39%) had ≥ 1 neuropsychiatric symptom. Poor executive function was associated with the presence of any symptoms and symptoms other than depression. More severe left frontal WMH was associated with depression. CONCLUSION: Executive dysfunction and left frontal WMH are correlated with neuropsychiatric symptoms in these patients.
Authors: Elles Douven; Sebastian Köhler; Maria M F Rodriguez; Julie Staals; Frans R J Verhey; Pauline Aalten Journal: Neuropsychol Rev Date: 2017-08-22 Impact factor: 7.444
Authors: Wai Kwong Tang; Chieh Grace Lau; Yan Liang; Lisha Wang; Vincent Mok; Oi Yan Yannie Soo; Wai Hong Thomas Leung; Gabor S Ungvari; Shinichiro Uchiyama; Jong S Kim Journal: J Am Heart Assoc Date: 2019-11-07 Impact factor: 5.501
Authors: Benny Zee; Yanny Wong; Jack Lee; Yuhua Fan; Jinsheng Zeng; Bonnie Lam; Adrian Wong; Lin Shi; Allen Lee; Chloe Kwok; Maria Lai; Vincent Mok; Alexander Lau Journal: Brain Commun Date: 2021-06-03