Literature DB >> 20844626

Monophasic synovial sarcoma presenting as mitral valve obstruction.

Warangkana Chokesuwattanaskul1, Jason Terrell, Leigh Ann Jenkins.   

Abstract

We report the case of a 26-year-old man who experienced progressive left-sided chest pain and 2 episodes of near-syncope. Studies revealed a 15-cm mass in the upper left lung, a 10-cm mass in the medial base of the left lung, and a 5-cm left atrial mass that involved the left lung, infiltrated the left pulmonary vein, and prolapsed into the mitral valve, causing intermittent obstruction. The patient underwent surgical excision of the left atrial tumor. Pathologic evaluation confirmed the diagnosis of monophasic synovial sarcoma.To our knowledge, this is only the 3rd report of left atrial invasion and resultant mitral valve obstruction from a synovial sarcoma that infiltrated the pulmonary vein. We believe that this is the 1st documented case of a metastatic left atrial synovial sarcoma in monophasic form.

Entities:  

Keywords:  Heart neoplasms/pathology/surgery; neoplasms/epidemiology; sarcoma, synovial/complications/diagnosis/genetics/pathology/radiotherapy/surgery/therapy/ultrasonography; thoracic neoplasms/surgery; tomography, X-ray computed; translocation, genetic/genetics

Mesh:

Year:  2010        PMID: 20844626      PMCID: PMC2929870     

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  15 in total

1.  Synovial sarcoma of the head and neck: chromosomal translation (X;18) as a diagnostic aid.

Authors:  R A Cihak; W M Lydiatt; D D Lydiatt; J A Bridge
Journal:  Head Neck       Date:  1997-09       Impact factor: 3.147

2.  Metastatic left atrial synovial sarcoma mimicking a myxoma.

Authors:  Sanjay Kumar; Mubarak A Chaudhry; Irfan Khan; David J R Duthie; Steve Lindsay; Pankaj Kaul
Journal:  J Thorac Cardiovasc Surg       Date:  2004-11       Impact factor: 5.209

Review 3.  Synovial sarcoma of the heart.

Authors:  A G Nicholson; M Rigby; C Lincoln; S Meller; C Fisher
Journal:  Histopathology       Date:  1997-04       Impact factor: 5.087

4.  Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype.

Authors:  Hans Martin Hazelbag; Károly Szuhai; Hans J Tanke; Carla Rosenberg; Pancras C W Hogendoorn
Journal:  Mod Pathol       Date:  2004-11       Impact factor: 7.842

5.  Synovial sarcoma outcome following conservation surgery and radiotherapy.

Authors:  J R Mullen; G K Zagars
Journal:  Radiother Oncol       Date:  1994-10       Impact factor: 6.280

Review 6.  Cardiac myxomas.

Authors:  K Reynen
Journal:  N Engl J Med       Date:  1995-12-14       Impact factor: 91.245

Review 7.  Cancer statistics, 2004.

Authors:  Ahmedin Jemal; Ram C Tiwari; Taylor Murray; Asma Ghafoor; Alicia Samuels; Elizabeth Ward; Eric J Feuer; Michael J Thun
Journal:  CA Cancer J Clin       Date:  2004 Jan-Feb       Impact factor: 508.702

8.  Intraarticular synovial sarcoma.

Authors:  C D McKinney; S E Mills; R E Fechner
Journal:  Am J Surg Pathol       Date:  1992-10       Impact factor: 6.394

9.  Calcifying synovial sarcoma.

Authors:  J Varela-Duran; F M Enzinger
Journal:  Cancer       Date:  1982-07-15       Impact factor: 6.860

10.  Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas.

Authors:  J H Edmonson; L M Ryan; R H Blum; J S Brooks; M Shiraki; S Frytak; D R Parkinson
Journal:  J Clin Oncol       Date:  1993-07       Impact factor: 44.544

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