Literature DB >> 20843430

Genotypic characterization of tuberculosis transmission within Toronto's under-housed population, 1997-2008.

H J Adam1, J L Guthrie, S Bolotin, D C Alexander, R Stuart, D Pyskir, E M Brown, E Rea, P Chedore, F B Jamieson.   

Abstract

Toronto has been the site of a recent extended tuberculosis (TB) outbreak in the homeless or under-housed population. Genotyping has identified a unique strain that continues to circulate within this population, with spread to individuals with no links to the shelter system, and anecdotally appears to progress rapidly from infection to active disease in some cases. The recent appearance and transmission of another unique strain was also identified, indicating that TB transmission continues to be a problem within the under-housed population. Enhanced surveillance utilizing molecular epidemiology is a useful tool to assist in TB control in vulnerable populations.

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Mesh：

Year:  2010        PMID： 20843430

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN： 1027-3719            Impact factor:   2.373


  7 in total

1.  Tuberculosis and homelessness in Montreal: a retrospective cohort study.

Authors:  Jason Tan de Bibiana; Carmine Rossi; Paul Rivest; Alice Zwerling; Louise Thibert; Fiona McIntosh; Marcel A Behr; Dick Menzies; Kevin Schwartzman
Journal:  BMC Public Health       Date:  2011-10-28       Impact factor: 3.295

2.  Marked microevolution of a unique Mycobacterium tuberculosis strain in 17 years of ongoing transmission in a high risk population.

Authors:  Carolina Mehaffy; Jennifer L Guthrie; David C Alexander; Rebecca Stuart; Elizabeth Rea; Frances B Jamieson
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

3.  Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion.

Authors:  Carla Duncan; Frances B Jamieson; JoLynn Troudt; Linda Izzo; Helle Bielefeldt-Ohmann; Angelo Izzo; Carolina Mehaffy
Journal:  PLoS One       Date:  2017-06-26       Impact factor: 3.240

4.  Universal genotyping reveals province-level differences in the molecular epidemiology of tuberculosis.

Authors:  Jennifer L Guthrie; Alex Marchand-Austin; Kirby Cronin; Karen Lam; Daria Pyskir; Clare Kong; Danielle Jorgensen; Mabel Rodrigues; David Roth; Patrick Tang; Victoria J Cook; James Johnston; Frances B Jamieson; Jennifer L Gardy
Journal:  PLoS One       Date:  2019-04-03       Impact factor: 3.240

5.  The problem with defining foreign birth as a risk factor in tuberculosis epidemiology studies.

Authors:  Jennifer L Guthrie; Lisa A Ronald; Victoria J Cook; James Johnston; Jennifer L Gardy
Journal:  PLoS One       Date:  2019-04-30       Impact factor: 3.240

6.  Preliminary evaluation of exome sequencing to identify genetic markers of susceptibility to tuberculosis disease.

Authors:  Carla Duncan; Frances Jamieson; Carolina Mehaffy
Journal:  BMC Res Notes       Date:  2015-12-08

7.  Universal Genotyping for Tuberculosis Prevention Programs: a 5-Year Comparison with On-Request Genotyping.

Authors:  Jennifer L Guthrie; Clare Kong; David Roth; Danielle Jorgensen; Mabel Rodrigues; Patrick Tang; Maichael Thejoe; Kevin Elwood; Victoria J Cook; James Johnston; Jennifer L Gardy
Journal:  J Clin Microbiol       Date:  2018-04-25       Impact factor: 5.948
  7 in total

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