Literature DB >> 20842876

[Current situation and prospect of treatment for radiation-induced lung injury].

Xin Li1, Jianxin Xue, You Lu.   

Abstract

Radiation-induced lung injury (RILI) is the most common complication of the radiotherapy for thoracic tumor. It can lower the ratio of local control and seriously affect the patients' quality of life. At present, the clinical management of RILI is not more than the use of glucocorticoid and anti-inflammatory agent for symptomatic treatments. These treatments do not have any preventive effect but cause much side reactions. In this paper, we review the data from the contigency researches on the mechanism of RILI, from the researches on gene therapy and stem cell-therapy, and we dicuss the more safe, more stable and more efficacious treatment of RILI.

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Year:  2010        PMID: 20842876

Source DB:  PubMed          Journal:  Sheng Wu Yi Xue Gong Cheng Xue Za Zhi        ISSN: 1001-5515


  2 in total

1.  Radiation-induced pulmonary injury accelerated pulmonary metastasis in a mouse model of breast cancer.

Authors:  Hong-Yun Gong; Wei-Guo Hu; Qin-Yong Hu; Xiang-Pan Li; Qi-Bin Song
Journal:  Oncol Lett       Date:  2015-10-16       Impact factor: 2.967

2.  Glucosamine protects against radiation-induced lung injury via inhibition of epithelial-mesenchymal transition.

Authors:  Xiao Lei; Na Ma; Yanjie Liang; Junyan Liu; Pei Zhang; Yanan Han; Wei Chen; Lehui Du; Baolin Qu
Journal:  J Cell Mol Med       Date:  2020-07-22       Impact factor: 5.310

  2 in total

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