Literature DB >> 20840111

Amniotic membrane transplantation for the treatment of feline corneal sequestrum: pilot study.

Laura Barachetti1, Chiara Giudice, Carlo M Mortellaro.   

Abstract

OBJECTIVES: To describe and evaluate the use of equine amniotic membrane trans-plantation after lamellar keratectomy for the treatment of corneal sequestrum in cats.
METHODS: Six cats (seven eyes) of various breed and ages with corneal sequestra were treated surgically with lamellar keratectomy and amniotic membrane transplantation. All the sequestra and a small piece of the amniotic membranes used for each surgery were submitted for histopathologic examination.
RESULTS: Five of the seven eyes showed minimal level of scarring in the cornea and good transparency. No recurrences of the sequestra have been noted during the follow-up period (3-9 months). One eye had necrosis of the amniotic membrane 2 weeks after the surgery. The sequestrum of this eye showed a high level of bacterial contamination on histopathology. Three months later the same cat developed a descemetocele in the area where the necrotic amniotic membrane was rejected. A second eye developed a perforation under the amniotic membrane two weeks after the surgery. The sequestrum of this eye was deep and without vascularization.
CONCLUSION: Amniotic membrane transplantation after lamellar keratectomy was a valid procedure for surgical treatment of corneal sequestrum in cats. The procedure resulted in excellent cosmesis and functional vision in five of seven eyes; although case selection is important, particularly to exclude the very deep and non-vascularized sequestra.

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Year:  2010        PMID: 20840111     DOI: 10.1111/j.1463-5224.2010.00821.x

Source DB:  PubMed          Journal:  Vet Ophthalmol        ISSN: 1463-5216            Impact factor:   1.644


  4 in total

1.  Diagnostic Ophthalmology. Corneal lesion in a cat.

Authors:  Lynne S Sandmeyer; Bianca S Bauer; Bruce H Grahn
Journal:  Can Vet J       Date:  2015-11       Impact factor: 1.008

2.  Lamellar Keratoplasty Using Acellular Bioengineering Cornea (BioCorneaVetTM) for the Treatment of Feline Corneal Sequestrum: A Retrospective Study of 62 Eyes (2018-2021).

Authors:  Huihao Xu; John S Sapienza; Yipeng Jin; Jiahao Lin; Xiaobo Zheng; Haodi Dong; Hongxiu Diao; Ying Zhao; Jiafeng Gao; Jing Tang; Xueqian Feng; Danielle Micceri; Haoran Zeng; Degui Lin
Journal:  Animals (Basel)       Date:  2022-04-13       Impact factor: 3.231

3.  Surgical treatment of canine and feline descemetoceles, deep and perforated corneal ulcers with autologous buccal mucous membrane grafts.

Authors:  Valentina Mezzadri; Alberto Crotti; Samanta Nardi; Giovanni Barsotti
Journal:  Vet Ophthalmol       Date:  2021-06-04       Impact factor: 1.444

4.  New Devitalized Freeze-Dried Human Umbilical Cord Amniotic Membrane as an Innovative Treatment of Ocular Surface Defects: Preclinical Results.

Authors:  Sophie Cognard; Laurence Barnouin; Justine Bosc; Florelle Gindraux; Marie-Claire Robin; Jean-Yves Douet; Gilles Thuret
Journal:  J Funct Biomater       Date:  2022-09-13
  4 in total

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