Literature DB >> 20838956

Bullous exudative retinal detachment due to infiltration of leukemic cells in a child with acute lymphoblastic leukemia.

Kenichi Yoshida1, Daisuke Hasegawa, Ayako Takusagawa, Itaru Kato, Chitose Ogawa, Nariaki Echizen, Kishiko Ohkoshi, Tatsuo Yamaguchi, Ryota Hosoya, Atsushi Manabe.   

Abstract

Acute lymphoblastic leukemia (ALL) is known to cause several ocular involvements, but exudative retinal detachment is a rare complication. We describe a case report of a 4-year-old boy with T cell ALL who developed bilateral exudative retinal detachment caused by leukemic infiltration in the retinas after achieving hematological remission. Intravenous steroid pulse therapy and local irradiation reversed the condition, but it recurred concurrently with disease progression after a second relapse in the bone marrow. It is suggested that ophthalmic examination is crucial for ALL patients, especially for those whose white blood cell count is very high at onset.

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Year:  2010        PMID: 20838956     DOI: 10.1007/s12185-010-0683-9

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  11 in total

1.  Serous retinal detachment caused by leukemic choroidal infiltration during complete remission.

Authors:  K Miyamoto; S Kashii; Y Honda
Journal:  Br J Ophthalmol       Date:  2000-11       Impact factor: 4.638

2.  Ophthalmic manifestations of leukemia.

Authors:  A P Schachat; J A Markowitz; D R Guyer; P J Burke; J E Karp; M L Graham
Journal:  Arch Ophthalmol       Date:  1989-05

3.  Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.

Authors:  Deborah A Thomas; Stefan Faderl; Jorge Cortes; Susan O'Brien; Francis J Giles; Steven M Kornblau; Guillermo Garcia-Manero; Michael J Keating; Michael Andreeff; Sima Jeha; Miloslav Beran; Srdan Verstovsek; Sherry Pierce; Laurie Letvak; August Salvado; Richard Champlin; Moshe Talpaz; Hagop Kantarjian
Journal:  Blood       Date:  2003-10-09       Impact factor: 22.113

4.  Retinopathy in acute leukaemia at initial diagnosis: correlation of fundus lesions and haematological parameters.

Authors:  S C Reddy; N Jackson
Journal:  Acta Ophthalmol Scand       Date:  2004-02

5.  Acute leukemia presenting as a unilateral exudative retinal detachment.

Authors:  M W Stewart; K A Gitter; G Cohen
Journal:  Retina       Date:  1989       Impact factor: 4.256

6.  Orbital and ocular manifestations of acute childhood leukemia: clinical and statistical analysis of 180 patients.

Authors:  V Russo; I U Scott; G Querques; A Stella; A Barone; N Delle Noci
Journal:  Eur J Ophthalmol       Date:  2008 Jul-Aug       Impact factor: 2.597

7.  Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15.

Authors:  Atsushi Manabe; Akira Ohara; Daisuke Hasegawa; Katsuyoshi Koh; Tomohiro Saito; Nobutaka Kiyokawa; Akira Kikuchi; Hiroyuki Takahashi; Koichiro Ikuta; Yasuhide Hayashi; Ryoji Hanada; Masahiro Tsuchida
Journal:  Haematologica       Date:  2008-06-02       Impact factor: 9.941

8.  Leukemic infiltration of the eye: results of therapy in a retrospective multicentric study.

Authors:  M L Curto; A Zingone; A Acquaviva; S Bagnulo; L Calculli; L Cristiani; G Dini; M T Di Tullio; C Guazzelli; M Jancovic
Journal:  Med Pediatr Oncol       Date:  1989

9.  Ocular involvement in childhood acute lymphoblastic leukemia.

Authors:  H Birinci; D Albayrak; I Oge; A Kaman
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2001 Jul-Aug       Impact factor: 1.402

10.  Retinal detachment in a child as the first sign of leukemic relapse: histopathology, MRI findings, treatment, and tumor-free follow up.

Authors:  J D Primack; M E Smith; L Tychsen
Journal:  J Pediatr Ophthalmol Strabismus       Date:  1995 Jul-Aug       Impact factor: 1.402

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  5 in total

1.  Unilateral bullous retinal detachment in a child with acute lymphoblastic leukaemia, and hypopyon as the first sign of leukaemic relapse.

Authors:  Sagili Chandrasekhara Reddy
Journal:  Int J Ophthalmol       Date:  2018-10-18       Impact factor: 1.779

2.  Relapsed T-cell acute lymphoblastic leukaemia in the vitreous of an adult: a case report.

Authors:  R Allchin; A Pradeep; R Sheard; I G Rennie; H S Mudhar
Journal:  Eye (Lond)       Date:  2014-05-09       Impact factor: 3.775

3.  Extramedullary Relapse of Acute Myelogenous Leukemia Presenting as a Large Serous Retinal Detachment.

Authors:  Wesley Green; P Kumar Rao; George J Harocopos
Journal:  Ocul Oncol Pathol       Date:  2016-11-08

4.  A 25-Year-Old Man with Exudative Retinal Detachments and Infiltrates without Hematological or Neurological Findings Found to Have Relapsed Precursor T-Cell Acute Lymphoblastic Leukemia.

Authors:  Jordan S Johnson; James S Lopez; Arthur Scott Kavanaugh; Chanping Liang; Douglas A Mata
Journal:  Case Rep Ophthalmol       Date:  2015-09-15

5.  Serous retinal detachment as a presenting sign of acute lymphoblastic leukemia: A case report and literature review.

Authors:  Malini Veerappan Pasricha; Natalia F Callaway; Quan Dong Nguyen; Diana V Do
Journal:  Am J Ophthalmol Case Rep       Date:  2021-06-22
  5 in total

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