Literature DB >> 20836683

DMBA-induced hamster buccal pouch carcinoma and VX2-induced rabbit cancer as a model for human oral carcinogenesis.

Yuk-Kwan Chen1, Li-Min Lin.   

Abstract

In this article, we have described and compared the advantages and disadvantages of two potential animal cancer models (the hamster buccal pouch cancer model and the VX2-induced rabbit cancer model) for human squamous cell carcinomas of the oral mucosa. Currently, no animal cancer model is perfectly applicable to human oral squamous cell carcinomas. This is because the hamster buccal pouch cancer model has a different etiology and genetic constitution compared with human oral carcinomas. In addition, the VX2-induced rabbit cancer model is not produced in situ and, consequently, its natural behavior is totally reliant on the location of transplantation. Nonetheless, with the use of these two animal cancer models together, researchers could evaluate different aspects of the cellular and molecular biological characteristics or assess potential novel treatment regimens for squamous cell carcinomas of the human oral mucosa.

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Year:  2010        PMID： 20836683     DOI： 10.1586/era.10.108

Source DB:  PubMed          Journal:  Expert Rev Anticancer Ther        ISSN： 1473-7140            Impact factor:   4.512


  10 in total

1.  Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new "B2" configuration of the RA-6 nuclear reactor.

Authors:  Andrea Monti Hughes; Juan Longhino; Esteban Boggio; Vanina A Medina; Diego J Martinel Lamas; Marcela A Garabalino; Elisa M Heber; Emiliano C C Pozzi; María E Itoiz; Romina F Aromando; David W Nigg; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2017-09-04       Impact factor: 1.925

2.  Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model.

Authors:  Marcela A Garabalino; Elisa M Heber; Andrea Monti Hughes; Sara J González; Ana J Molinari; Emiliano C C Pozzi; Susana Nievas; Maria E Itoiz; Romina F Aromando; David W Nigg; William Bauer; Verónica A Trivillin; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2013-04-17       Impact factor: 1.925

Review 3.  Engineering Polymeric Nanosystems against Oral Diseases.

Authors:  Valeria Mercadante; Edoardo Scarpa; Valeria De Matteis; Loris Rizzello; Alessandro Poma
Journal:  Molecules       Date:  2021-04-13       Impact factor: 4.411

Review 4.  Animal models for periodontal disease.

Authors:  Helieh S Oz; David A Puleo
Journal:  J Biomed Biotechnol       Date:  2011-02-10

5.  Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models.

Authors:  Nidal Muhanna; Cheng S Jin; Elizabeth Huynh; Harley Chan; Yi Qiu; Wenlei Jiang; Liyang Cui; Laura Burgess; Margarete K Akens; Juan Chen; Jonathan C Irish; Gang Zheng
Journal:  Theranostics       Date:  2015-10-18       Impact factor: 11.556

6.  Orthotopic VX rabbit tongue cancer model with FDG-PET and histologic characterization.

Authors:  Brendan C Stack; John Ye; Twyla B Bartel; Gal Shafirstein; Chien Chen; Eric Siegel; Bipin Singh; Samta Thacker; Val J Lowe; Vivek Nagarkar
Journal:  Head Neck       Date:  2012-09-18       Impact factor: 3.147

7.  The promoting effect of carbamide peroxide teeth bleaching gel in a preclinical model of head and neck cancer in hamster buccal pouch.

Authors:  Vinícius Faccin Bampi; Wadson Ferreira Vilela; Reggiani Vilela Gonçalves; Maria Gabriela Tavares Rheingantz; Luiz Fernando Minello; Jefferson Luis Braga da Silva; Laura Beatriz Oliveira de Oliveira
Journal:  Clin Exp Otorhinolaryngol       Date:  2014-08-01       Impact factor: 3.372

8.  Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma.

Authors:  Yuk-Kwan Chen; Anderson Hsien-Cheng Huang; Li-Min Lin
Journal:  Int J Oral Sci       Date:  2014-07-11       Impact factor: 6.344

9.  Salivary Exosome Proteomics and Bioinformatics Analysis in 7,12-Dimethylbenz[a]anthracene-Induced Oral Cancer with Radiation Therapy-A Syrian Golden Hamster Model.

Authors:  Wen-Chen Wang; Ming-Yii Huang; Yuk-Kwan Chen; Wan-Chen Lan; Tzong-Ming Shieh; Yin-Hwa Shih
Journal:  Diagnostics (Basel)       Date:  2021-12-28

10.  Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer.

Authors:  Liang-Tzung Lin; Ying-Jang Lai; She-Ching Wu; Wei-Hsuan Hsu; Chen-Jei Tai
Journal:  J Food Drug Anal       Date:  2017-02-16       Impact factor: 6.157
  10 in total

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