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Literature DB >> 2083512

Current concepts in the treatment of immune thrombocytopenia.

Abstract

Platelet destruction by antibodies is a common cause of thrombocytopenia. In this review, various treatments for immune thrombocytopenia are discussed, with emphasis on corticosteroids, splenectomy, danazol, high-dose immunoglobulin G, anti-Rhesus globulin, colchicine and cytotoxic, immunosuppressive agents such as cyclophosphamide and azathioprine. An approach to the treatment of adult idiopathic thrombocytopenic purpura (ITP) is reviewed in detail and the treatments for several other immune thrombocytopenic disorders are summarised.

Entities: Chemical Disease

Mesh：

Year: 1990 PMID： 2083512 DOI： 10.2165/00003495-199040040-00004

Source DB: PubMed Journal: Drugs ISSN： 0012-6667 Impact factor: 9.546

100 in total

1. Urgent treatment of idiopathic thrombocytopenic purpura with single-dose gammaglobulin infusion followed by platelet transfusion.

Authors: M A Baumann; J E Menitove; R H Aster; T Anderson
Journal: Ann Intern Med Date: 1986-06 Impact factor: 25.391

2. Re-evaluation of the role of azathioprine in the treatment of adult chronic idiopathic thrombocytopenic purpura: a report on 53 cases.

Authors: I Quiquandon; P Fenaux; M T Caulier; D Pagniez; J J Huart; F Bauters
Journal: Br J Haematol Date: 1990-02 Impact factor: 6.998

3. Effect of IgG anti-Rho(D) in adult patients with chronic autoimmune thrombocytopenia.

Authors: A Salama; V Kiefel; C Mueller-Eckhardt
Journal: Am J Hematol Date: 1986-07 Impact factor: 10.047

4. Anti-idiotypic suppression of autoantibodies to factor VIII (antihaemophilic factor) by high-dose intravenous gammaglobulin.

Authors: Y Sultan; M D Kazatchkine; P Maisonneuve; U E Nydegger
Journal: Lancet Date: 1984-10-06 Impact factor: 79.321

5. Treatment of idiopathic thrombocytopenic purpura in adults. Long-term results in a series of 41 patients.

Authors: E Ikkala; E Kivilaakso; M Kotilainen; J Hästbacka
Journal: Ann Clin Res Date: 1978-04

6. Adverse effects of danazol in pregnancy.

Authors: A C Wentz
Journal: Ann Intern Med Date: 1982-05 Impact factor: 25.391

7. Improvement of platelet counts in steroid-unresponsive idiopathic immune thrombocytopenic purpura after short-course therapy with recombinant alpha 2b interferon.

Authors: S J Proctor; G Jackson; P Carey; A Stark; R Finney; P Saunders; G Summerfield; D Maharaj; A Youart
Journal: Blood Date: 1989-11-01 Impact factor: 22.113

8. Therapeutic experience on 934 adults with idiopathic thrombocytopenic purpura: Multicentric Trial of the Cooperative Latin American group on Hemostasis and Thrombosis.

Authors: J Pizzuto; R Ambriz
Journal: Blood Date: 1984-12 Impact factor: 22.113

9. Treatment of heparin-associated thrombocytopenia and thrombosis with low molecular weight heparin (CY 216).

Authors: J Leroy; M H Leclerc; B Delahousse; C Guérois; P Foloppe; Y Gruel; F Toulemonde
Journal: Semin Thromb Hemost Date: 1985-07 Impact factor: 4.180

10. Antenatal treatment of neonatal alloimmune thrombocytopenia.

Authors: J B Bussel; R L Berkowitz; J G McFarland; L Lynch; U Chitkara
Journal: N Engl J Med Date: 1988-11-24 Impact factor: 91.245

3 in total

Review 1. [Chronic idiopathic thrombocytopenic purpura. Current therapy concept and introduction to pathophysiologic, clinical and diagnostic aspects].

Authors: A Böcher; F G Hagmann; H Kreiter
Journal: Med Klin (Munich) Date: 1998-12-15

2. Immune thrombocytopenia associated with hemorrhagic diathesis due to ibuprofen administration.

Authors: T Meyer; C Herrmann; V Wiegand; B Mathias; V Kiefel; C Mueller-Eckhardt
Journal: Clin Investig Date: 1993-05

3. Acute airway obstruction by laryngeal haematomas in acute immune thrombocytopenic purpura.

Authors: T C Aiken; R C Collin
Journal: Postgrad Med J Date: 1996-04 Impact factor: 2.401

3 in total