BACKGROUND: Pre-menstrual dysphoric disorder (PMDD), a dysphoric form of pre-menstrual syndrome, is included as a diagnosis for further study in the DSM-IV-TR (APA, 2000). The present study investigated whether a marker of risk for major depressive disorder (MDD), prefrontal brain asymmetry, also characterizes women with PMDD. METHODS: In a sample of 25 college women with PMDD symptomatology and 25 matched controls, resting frontal electroencephalographic (EEG) activity was assessed on four occasions within a two-week span. RESULTS: Across several frontal sites women with PMDD had relatively less left than right prefrontal brain activity, consistent with a diathesis-stress model for menstrual-related dysphoria. CONCLUSIONS: The findings suggest an overlap in the risk profile for MDD and PMDD. Published by Elsevier B.V.
BACKGROUND: Pre-menstrual dysphoric disorder (PMDD), a dysphoric form of pre-menstrual syndrome, is included as a diagnosis for further study in the DSM-IV-TR (APA, 2000). The present study investigated whether a marker of risk for major depressive disorder (MDD), prefrontal brain asymmetry, also characterizes women with PMDD. METHODS: In a sample of 25 college women with PMDD symptomatology and 25 matched controls, resting frontal electroencephalographic (EEG) activity was assessed on four occasions within a two-week span. RESULTS: Across several frontal sites women with PMDD had relatively less left than right prefrontal brain activity, consistent with a diathesis-stress model for menstrual-related dysphoria. CONCLUSIONS: The findings suggest an overlap in the risk profile for MDD and PMDD. Published by Elsevier B.V.
Authors: M Steiner; S Steinberg; D Stewart; D Carter; C Berger; R Reid; D Grover; D Streiner Journal: N Engl J Med Date: 1995-06-08 Impact factor: 91.245
Authors: Olle Eriksson; Anders Wall; Ulf Olsson; Ina Marteinsdottir; Maria Holstad; Hans Ågren; Per Hartvig; Bengt Långström; Tord Naessén Journal: PLoS One Date: 2016-09-12 Impact factor: 3.240