| Literature DB >> 20832916 |
Shailaja Myadaraboina1, Manjula Alla, Venkateshwarlu Saddanapu, Vittal Rao Bommena, Anthony Addlagatta.
Abstract
Designed novel imidazo[1,2-a]pyrazine based inhibitors, synthesized by condensing α-aminopyrazines with α-halocarbonyl compounds followed by electrophilic substitutions. Cytotoxic effects on four cancer cell lines evaluated. Based on preliminary data, imidazo[1,2-a]pyrazine template redesigned to improve activity.Entities:
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Year: 2010 PMID： 20832916 DOI： 10.1016/j.ejmech.2010.08.035
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514